861597-64-0Relevant academic research and scientific papers
Synthesis of N-alkyl-Cα,α-dimethylglycine derivatives
Monteiro, Luis S.,Pereira-Lima, Silvia M.M.A.,Pereira, Sofia,Machado, Joao N.
, p. 170 - 180 (2014/10/15)
The application of trialkyloxonium tetrafluoroborates for N-alkylation of the nonnatural amino acid Cα, α-dimethylglycine is described. Several methyl esters of dimethylglycine protected with different amine protecting groups were subject to N-
The use of tetrabutylammonium fluoride to promote N- and O- 11C-methylation reactions with iodo[11C]methane in dimethyl sulfoxide
Kikuchi, Tatsuya,Minegishi, Katsuyuki,Hashimoto, Hiroki,Zhang, Ming-Rong,Kato, Koichi
, p. 672 - 678 (2014/01/06)
The N- or O-methylation reactions of compounds bearing amide, aniline, or phenol moieties using iodo[11C]methane (1) with the aid of a base are frequently applied to the preparation of 11C-labeled radiopharmaceuticals. Although sodiu
