53617-94-0 Usage
Uses
Used in Pharmaceutical Industry:
Alanine, N,2-dimethyl-, methyl ester (9CI) is used as a building block in the synthesis and preparation of various pharmaceuticals. Its unique structure allows for the creation of new drugs and therapeutic agents, contributing to the advancement of medical treatments.
Used in Agrochemical Industry:
Alanine, N,2-dimethyl-, methyl ester (9CI) is also utilized in the agrochemical industry, where it serves as a key component in the development of bioactive compounds. Its versatility in chemical reactions enables the production of effective agrochemicals for various applications.
Used in Organic Synthesis:
Alanine, N,2-dimethyl-, methyl ester (9CI) is employed as a reagent in organic synthesis, where it contributes to the formation of complex organic molecules. Its presence in these reactions aids in the development of novel chemical compounds with diverse applications.
Used in Chemical Research:
In the field of chemical research, Alanine, N,2-dimethyl-, methyl ester (9CI) is used for its potential in modifying proteins and peptides. Its unique properties make it a valuable tool for studying protein structure and function, as well as for developing new methods in protein engineering.
It is important to handle and use Alanine, N,2-dimethyl-, methyl ester (9CI) with care, following proper safety and handling guidelines to ensure the safety of both the users and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 53617-94-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,6,1 and 7 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 53617-94:
(7*5)+(6*3)+(5*6)+(4*1)+(3*7)+(2*9)+(1*4)=130
130 % 10 = 0
So 53617-94-0 is a valid CAS Registry Number.
53617-94-0Relevant academic research and scientific papers
Trimethyl-substituted carbamate as a versatile self-immolative linker for fluorescence detection of enzyme reactions
Inoue, Kazuya,Nakamura, Noriaki,Ojida, Akio,Uchinomiya, Shohei
supporting information, (2020/05/25)
Self-immolative linker is a useful building block of molecular probes, with broad applications in the fields of enzyme activity analysis, stimuli-responsive material science, and drug delivery. This manuscript presents N-methyl dimethyl methyl (i.e., trimethyl) carbamate as a new class of self-immolative linker for the fluorescence detection of enzyme reactions. The trimethyl carbamate was shown to spontaneously undergo intramolecular cyclization upon formation of a carboxylate group, to liberate a fluorophore with the second time rapid reaction kinetics. Interestingly, the auto-cleavage reaction of trimethyl carbamate was also induced by the formation of hydroxyl and amino groups. Fluorescent probes with a trimethyl carbamate could be applicable for fluorescence monitoring of the enzyme reactions catalyzed by esterase, ketoreductase, and aminotransferase, and for fluorescence imaging of intracellular esterase activity in living cells, hence demonstrating the utility of this new class of self-immolative linker.
COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2
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Paragraph 00304, (2018/01/21)
The present invention relates to compounds of formula I: in which Y1, Y2, R1, R2 and R3 are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.
