861631-61-0

Basic information

• Product Name: methyl 3-[(E)-2-(2-methoxyquinolin-3-yl)vinyl]-4-nitrobenzoate
• Synonyms: methyl 3-[(E)-2-(2-methoxyquinolin-3-yl)vinyl]-4-nitrobenzoate
• CAS NO: 861631-61-0
• Molecular Weight: 364.357
• Mol File: 861631-61-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 3-[(E)-2-(2-methoxyquinolin-3-yl)vinyl]-4-nitrobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-[(E)-2-(2-methoxyquinolin-3-yl)vinyl]-4-nitrobenzoate(861631-61-0)
• EPA Substance Registry System: methyl 3-[(E)-2-(2-methoxyquinolin-3-yl)vinyl]-4-nitrobenzoate(861631-61-0)

Safety Data

• Hazardous Substances Data: 861631-61-0(Hazardous Substances Data)

Upstream product

• 139549-06-7 2-methoxy-3-quinolinecarboxyaldehyde 
• 24078-21-5 methyl 3-methyl-4-nitrobenzoate 
• 851777-21-4 methyl 3-[2-hydroxy-2-(2-methoxyquinolin-3-yl)ethyl]-4-nitrobenzoate 

Relevant articles and documents

A highly active catalyst for the reductive cyclization of ortho-nitrostyrenes under mild conditions

A mild and efficient method for the palladium-catalyzed reductive cyclization of ortho-nitrostyrenes to afford indoles is reported. Treatment of ortho-nitrostyrenes with 0.1 mol% palladium (II) trifluoroacetate [Pd(TFA) 2] and 0.7 mol% 3,4,7,8-tetramethyl-1,10-phenanthroline (tm-phen) in DMF at 15 psig CO and 80°C afforded indoles in good to excellent yields. When the reaction was conducted in toluene, the corresponding N-hydroxyindole was isolated. A mechanism that accounts for the formation of N-hydroxyindole is proposed.