861676-03-1Relevant articles and documents
Chemoenzymatic synthesis of the polyketide macrolactone 10-deoxymethynolide
Aldrich, Courtney C.,Venkatraman, Lakshmanan,Sherman, David H.,Fecik, Robert A.
, p. 8910 - 8911 (2007/10/03)
The polyketide synthase-derived pikromycin thioesterase (Pik TE) is unique in its ability to catalyze the cyclization of 12- and 14-membered macrolactones. In this investigation, the total synthesis of the natural hexaketide chain elongation intermediate