861822-01-7Relevant academic research and scientific papers
Total synthesis and biological evaluation of C16 analogs of (-)-dictyostatin
Jung, Won-Hyuk,Harrison, Cristian,Shin, Youseung,Fournier, Jean-Hugues,Balachandran, Raghavan,Raccor, Brianne S.,Sikorski, Rachel P.,Vogt, Andreas,Curran, Dennis P.,Day, Billy W.
, p. 2951 - 2966 (2008/02/08)
The structure-activity relationship of the crucial C16 region of (-)-dictyostatin was established through total synthesis of analogs followed by detailed biological characterization. A versatile synthetic strategy was used to prepare milligram quantities
