862261-25-4 Usage
Molecular Weight
355.29 g/mol
Spiro-lactone ring
A cyclic structure containing a lactone (ester) group connected to a spiro carbon atom.
1,4-Dioxa-8-aza
Indicates the presence of two oxygen atoms and one nitrogen atom in the ring structure.
8-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]
A phenyl group (C6H5) attached to the spiro-lactone ring at the 8th position, with a boron-containing group (1,3,2-dioxaborolane) as a substituent.
Lactone
A cyclic ester with a carbonyl group and an ester group in the same ring.
Ester
A functional group formed by the reaction of an acid and an alcohol, with the general formula RCOOR'.
Phenyl
A six-membered aromatic ring with alternating single and double carbon-carbon bonds.
Boron-containing group
A group containing the element boron, which can be used for various synthetic applications.
Organic synthesis
Used as a building block for creating new molecules with potential biological activities.
Pharmaceutical research
Employed in drug discovery and development due to its unique structure and functional groups.
Proper handling
Follow standard laboratory procedures and guidelines when working with this compound.
Minimize exposure
Use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats to reduce the risk of exposure.
Potential hazards
Be aware of the compound's potential hazards, such as flammability, toxicity, or reactivity with other chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 862261-25-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,2,2,6 and 1 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 862261-25:
(8*8)+(7*6)+(6*2)+(5*2)+(4*6)+(3*1)+(2*2)+(1*5)=164
164 % 10 = 4
So 862261-25-4 is a valid CAS Registry Number.
862261-25-4Relevant articles and documents
2-(2-Furanyl)-7-phenyl[1,2,4]triazolo[1,5-c]pyrimidin-5-amine analogs as adenosine A2A antagonists: The successful reduction of hERG activity. Part 2
Matasi, Julius J.,Caldwell, John P.,Zhang, Hongtao,Fawzi, Ahmad,Higgins, Guy A.,Cohen-Williams, Mary E.,Varty, Geoffrey B.,Tulshian, Deen B.
, p. 3675 - 3678 (2007/10/03)
The structure-activity relationship (SAR) exploration using 2-(2-furanyl)-7-phenyl[1,2,4]triazolo-[1,5-c]pyrimidin-5-amine (1) as a template led to the identification of a novel class of potent and selective adenosine A2A receptor (AR) antagoni