945732-97-8

Basic information

• Product Name: 3-(1,4-dioxa-8-aza-spiro[4.5]decen-8-yl)-phenol
• Synonyms: 3-(1,4-dioxa-8-aza-spiro[4.5]decen-8-yl)-phenol
• CAS NO: 945732-97-8
• Molecular Weight: 235.283
• Mol File: 945732-97-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(1,4-dioxa-8-aza-spiro[4.5]decen-8-yl)-phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1,4-dioxa-8-aza-spiro[4.5]decen-8-yl)-phenol(945732-97-8)
• EPA Substance Registry System: 3-(1,4-dioxa-8-aza-spiro[4.5]decen-8-yl)-phenol(945732-97-8)

Safety Data

• Hazardous Substances Data: 945732-97-8(Hazardous Substances Data)

Upstream product

• 591-20-8 3-Bromophenol 
• 177-11-7 4,4-ethylenedioxy-piperidine 
• 571202-87-4 3-bromophenyl triisopropylsilyl ether 
• 862261-24-3 8-(3-triisopropylsilanyloxy-phenyl)-1,4-dioxa-8-aza-spiro[4.5]decane 

Downstream Products

• 540751-94-8 1-[3-(5-amino-2-furan-2-yl-[1,2,4]triazolo[1,5-c]pyrimidin-7-yl)-phenyl]-piperidin-4-one 
• 862261-26-5 4-chloro-6-[3-(1,4-dioxa-8-aza-spiro[4.5]dec-8-yl)-phenyl]-pyrimidin-2-ylamine 
• 862261-25-4 8-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-1,4-dioxa-8-aza-spiro[4.5]decane 

Relevant articles and documents

TRIAZOLE DERIVATIVE

An object of the present invention is to provide a compound having an action of inhibiting binding between S1P and its receptor, Edg-1 (S1P1), and is useful as a pharmaceutical compound. A compound or a pharmaceutically acceptable salt thereof, which compound is represented by the formula below (where A represents an oxygen atom, a sulfur atom, a group represented by Formula -SO-, a group represented by Formula -SO2-, or the like, R1 represents a hydrogen atom, an alkyl group having 1-6 carbon atoms, or the like, R1A represents a hydrogen atom or the like, R2 represents an alkyl group having 1-6 carbon atoms, a cycloalkyl group having 3-6 carbon atoms, or the like, R3 represents an aryl group, R4 represents a hydrogen atom or an alkyl group having 1-6 carbon atoms and optionally substituted with a carboxyl group, and R5 represents an alkyl group having 1-10 carbon atoms, a cycloalkyl group having 3-8 carbon atoms, an aryl group which is optionally substituted, or the like).