862283-69-0

Usage

Uses

Used in Pharmaceutical Industry:
Trans-Methyl 1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylate is used as an intermediate in the synthesis of various pharmaceuticals for its unique chemical properties and potential applications in chemical and pharmaceutical processes.
Used in Organic Compounds Synthesis:
Trans-Methyl 1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylate is also used as an intermediate in the synthesis of other organic compounds, contributing to the development of new chemical entities and materials.
It is important to handle Trans-Methyl 1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carboxylate with caution due to potential health and safety risks if not used properly.

Upstream product

• 35086-79-4 cinnamoyl chloride 
• 1615-02-7 3-(4-chlorophenyl)prop-2-enoic acid 
• 1310819-13-6 (3R,4R)-1-benzyl-4-(4-chloro-phenyl)-pyrrolidine-3-carboxylic acid methyl ester 
• 637-87-6 1-Chloro-4-iodobenzene 
• 1310819-12-5 (3R,4R)-1-benzyl-4-(4-chloro-phenyl)-pyrrolidine-3-carboxylic acid 
• 1229236-32-1 1-Benzyl-4-(4-chloro-phenyl)-2,5-dihydro-1H-pyrrole-3-carboxylic acid 
• 20026-96-4 ethyl 3-(4-chlorophenyl)propiolate 
• 93102-05-7 N-benzyl-N-(methoxymethyl)-N-[(trimethylsilyl)methyl]amine 
• 862283-67-8 (S)-4-benzyl-3-((3S,4R)-1-benzyl-4-(4-chlorophenyl)pyrrolidine-3-carbonyl)oxazolidin-2-one 
• 616-38-6 carbonic acid dimethyl ester 

Downstream Products

• 1310819-14-7 (3S,4R)-1-benzyl-4-(4-chloro-phenyl)-pyrrolidine-3-carboxylic acid amide 
• 1310819-15-8 [(3S,4R)-1-benzyl-4-(4-chloro-phenyl)-pyrrolidin-3-yl]-carbamic acid methyl ester 
• 1310819-51-2 [(3S,4R)-1-benzyl-4-(4-chloro-phenyl)-pyrrolidin-3-yl]-methyl-carbamic acid tert-butyl ester 
• 1310819-16-9 [(3S,4R)-1-benzyl-4-(4-chloro-phenyl)-pyrrolidin-3-yl]-methyl-amine 
• 862283-71-4 (3S,4R)-methyl 4-(4-chlorophenyl)pyrrolidine-3-carboxylate hydrochloride 

Relevant academic research and scientific papers

Structure-based design of potent and selective leishmania N -myristoyltransferase inhibitors

Inhibitors of Leishmania N-myristoyltransferase (NMT), a potential target for the treatment of leishmaniasis, obtained from a high-throughput screen, were resynthesized to validate activity. Crystal structures bound to Leishmania major NMT were obtained,

PYRROLIDINE DERIVATIVES

The present invention relates to compounds of formula wherein R1, R2, R3, R4, Z, and n are as defined herein or to a pharmaceutically active salt thereof. Compounds of the invention are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).

PYRROLIDINE DERIVATIVES

The present invention relates to compounds of formula (I) or to a pharmaceutically active salt thereof. It has been found that the present compounds are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's

Pharmaceutically active compounds

The present invention relates to a class of melanocortin MCR4 agonists of general formula (I) wherein R1, R2, R3, R4 and R5 are as defined herein and especially to selective MCR4 agonist compounds, to