86241-19-2

Usage

Uses

Used in Pharmaceutical Research:
[BIS-(2-HYDROXY-ETHYL)-AMINO]-ACETONITRILE is used as a reagent for the preparation of various pharmaceuticals and organic compounds. Its unique structure allows it to be a valuable component in the development of new drugs and medications.
Used in Organic Synthesis:
In the field of organic chemistry, [BIS-(2-HYDROXY-ETHYL)-AMINO]-ACETONITRILE serves as a key intermediate in the synthesis of complex organic molecules. Its ability to form stable bonds with other compounds makes it a useful building block for creating a wide range of chemical products.
Used in Coordination Chemistry:
[BIS-(2-HYDROXY-ETHYL)-AMINO]-ACETONITRILE has been studied for its potential as a chelating agent, which can form multiple bonds with a central metal ion. This property makes it a candidate for use in the development of new coordination compounds with potential applications in various industries.
Used in Laboratory Settings:
As a flammable liquid, [BIS-(2-HYDROXY-ETHYL)-AMINO]-ACETONITRILE requires careful handling in laboratory environments. Its use in research and development is essential for advancing the understanding of its properties and potential applications in various fields.
Overall, [BIS-(2-HYDROXY-ETHYL)-AMINO]-ACETONITRILE is a versatile and valuable chemical compound with a wide range of applications in the fields of pharmaceutical research, organic synthesis, coordination chemistry, and laboratory settings.

Upstream product

• 20073-50-1 2-(oxazolidin-3-yl)ethanol 
• 74-90-8 hydrogen cyanide 
• 107-14-2 chloroacetonitrile 
• 111-42-2 2,2'-iminobis[ethanol] 
• 590-17-0 cyanomethyl bromide 

Downstream Products

• 3197-06-6 N,N-bis(2-hydroxyethyl)ethylidenediamine 

Relevant academic research and scientific papers

POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS

A positive resist composition comprises (A) a resin component which becomes soluble in an alkaline developer under the action of an acid and (B) an acid generator. The resin (A) is a polymer comprising recurring units containing a non-leaving hydroxyl group represented by formula (1) wherein R1 is H, methyl or trifluoromethyl, X is a single bond or methylene, m is 1 or 2, and the hydroxyl group attaches to a secondary carbon atom. The composition is improved in resolution when processed by lithography.

Novel tertiary (meth)acrylates having lactone structure, polymers, resist compositions and patterning process

Novel tertiary (meth)acrylate compounds having a lactone structure are polymerizable into polymers having improved transparency, especially at the exposure wavelength of an excimer laser and dry etching resistance. Resist compositions comprising the polymers are sensitive to high-energy radiation, have a high resolution, and lend themselves to micropatterning with electron beams or deep-UV rays.

Amine compounds, resist compositions and patterning process

Amine compounds having a cyano group are useful in resist compositions for preventing a resist film from thinning and also for enhancing the resolution and focus margin of resist.

Synthesis and DNA-Sequence Selectivity of a Series of Mono- and Difunctional 9-Aminoacridine Nitrogen Mustards

The aim of this work was to identify nitrogen mustards that would react selectively with DNA, particularly in G-rich regions.A series of mono- and difunctional nitrogen mustards was synthesized in which the (2-chloroethyl)amino functions were connected to the N9 of 9-aminoacridine by way of a spacer chain consisting of two to six methylene units.The length of the spacer chain connecting the alkylating and putative DNA-intercalating groups was found to affect the preference for the alkylation of different guanine-N7 positions in a DNA sequence.All of the compounds reacted preferentially at G's that are followed by G as do most other types of nitrogen mustards, but the degree of selectivity was greater.The compounds reacted at much lower concentrations than were required for comparable reaction by mechlorethamine (HN2), consistent with initial noncovalent binding to DNA prior to guanine-N7 alkylation.The degree of DNA-sequance selectivity increased as the spacer-chain length decrease below four methylene units.Most strikingly, long spacer compounds reacted strongly at 5'-GT-3' sequences, whereas this reaction was almost completely suppressed when the spacer length was reduced to two or three methylenes.Mono- and difunctional compounds of a given spacer length showed no consistent difference in DNA-sequence preference.

Intermediates for the production of diethanolamine

A method of producing diethanolamine derivatives or acid salts thereof according to the reaction scheme: STR1 wherein X stands for a leaving group; and R1 stands for an alkylcarbamoyl group, which provides an industrially advantageous method of preparing the subject matter useful as an antiarrhythmic agent.