862416-37-3 Usage
Uses
Used in Pharmaceutical Research:
1-Benzyl-3,3-difluoropyrrolidine hydrochloride is used as a building block for the synthesis of drug molecules due to its unique chemical structure and reactivity, contributing to the development of novel therapeutic agents.
Used in Central Nervous System Disorders:
BDPFH is used as a potential treatment for various neurological and psychiatric conditions because of its demonstrated biological activities and promising properties in this field, making it a significant target for further research and drug development.
Used in Drug Solubility Enhancement:
The hydrochloride salt form of 1-benzyl-3,3-difluoropyrrolidine hydrochloride is used to improve the solubility of the compound in aqueous solutions, which is crucial for its handling, administration, and bioavailability in both laboratory and clinical settings.
Check Digit Verification of cas no
The CAS Registry Mumber 862416-37-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,2,4,1 and 6 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 862416-37:
(8*8)+(7*6)+(6*2)+(5*4)+(4*1)+(3*6)+(2*3)+(1*7)=173
173 % 10 = 3
So 862416-37-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H13F2N.ClH/c12-11(13)6-7-14(9-11)8-10-4-2-1-3-5-10;/h1-5H,6-9H2;1H
862416-37-3Relevant academic research and scientific papers
Xu, Feng,Simmons, Bryon,Armstrong III, Joseph,Murry, Jerry
, p. 6105 - 6107 (2005)
A practical and cost-effective synthesis of 3,3-difluoropyrrolidine is reported. The synthesis involves the isolation of two intermediates, which are prepared via two efficient through processes: (1) a Claisen rearrangement followed by a Ru(VIII)-catalyzed oxidation to prepare the 2,2-difluorosuccinic acid and (2) an efficient cyclization to form N-benzyl-3,3-difluoropyrrolidinone followed by BH3·Me2S reduction.
