862421-95-2

Upstream product

• 186581-53-3 diazomethane 
• 179087-83-3 (S)-2-tert-butoxycarbonylamino-3-phenylselanylpropionic acid 
• 1666-13-3 diphenyl diselenide 
• 175844-11-8 methyl (2R)-2-[(tert-butoxycarbonyl)amino]-3-bromopropionate 
• 126496-79-5 (S)-N-tert-butoxycarbonyl aziridine-2-carboxylate methyl ester 
• 3262-72-4 (S)-N-(tert-butoxycarbonyl)serine 
• 56926-94-4 methyl (2S)-2-[N-(t-butoxycarbonyl)amino]-3-(4-methylbenzenesulfonyl)-oxypropionate 
• 23974-72-3 sodium phenylselenide 
• 98541-64-1 (S)-3-(tert-butoxycarbonylamino)-oxetan-2-one 
• 187035-34-3 (S)-2-tert-butoxycarbonylamino-3-methanesulfonyloxypropionic acid methyl ester 
• 2766-43-0 N-tert-butyloxycarbonyl-L-serine methyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 71128-82-0 L-(Se)-phenylselenocysteine 
• 179087-83-3 (S)-2-tert-butoxycarbonylamino-3-phenylselanylpropionic acid 

Relevant academic research and scientific papers

Chiral seleno-amines from indium selenolates. A straightforward synthesis of selenocysteine derivatives

A simple and efficient procedure for the synthesis of chiral β-seleno-amines derivatives from a one-pot indium(I) iodide-mediated aziridine ring opening with diorganoyl diselenides has been developed. As an application, the synthesis of selenocysteine and

Zn in ionic liquid: An efficient reaction media for the synthesis of diorganyl chalcogenides and chalcogenoesters

A straightforward and efficient methodology is described to synthesize structurally diverse diorganyl selenides, sulfides, seleno- and thioesters by using commercially available Zn dust in ionic liquid. Excellent yields were achieved under neutral conditions at room temperature in a short time. The solvent/ionic liquid is reusable and exhibited higher performance as compared with organic solvents.

Synthesis of diorganyl selenides mediated by zinc in ionic liquid

Figure presented A new approach for the synthesis of diorganyl selenides is described. By using economically attractive zinc dust in BMIM-BF4, a series of diorganyl selenides were efficiently achieved in excellent yields, under neutral reaction conditions. Compared to the usual organic solvents, BMIM-BF4 exhibited higher performance with the advantage to be reused up to five successive runs.

Straightforward method for the synthesis of selenocysteine and selenocystine derivatives from L-serine methyl ester

A set of selenoamino acids has been efficiently synthesized under smooth conditions by a simple, flexible and modular strategy. In this method, O-mesylated l-serine methyl ester is generated in situ and directly substituted with various selenolate anions

Internally stabilized selenocysteine derivatives: Syntheses, 77Se NMR and biomimetic studies

Selenocystine ([Sec]2) and aryl-substituted selenocysteine (Sec) derivatives are synthesized, starting from commercially available amino acid L-serine. These compounds are characterized by a number of analytical techniques such as NMR (1H, 13C and 77Se) and TOF mass spectroscopy. This study reveals that the introduction of amino/imino substituents capable of interacting with selenium may stabilize the Sec derivatives. This study further suggests that the oxidation-elimination reactions in Sec derivatives could be used for the generation of biologically active selenols having internally stabilizing substituents. The Royal Society of Chemistry 2005.

Synthesis of optically pure β-phenylselenoalanine through serine-β-lactone: A useful precursor of dehydroalanine

Optically pure L- and D-β-phenylselenoalanines (PhSeAla), useful precursors of dehydroalanine, were synthesized from L- and D-serine-β-lactone. Elimination reactions of the phenylseleno group to form the dehydroalanine were examined.