862468-65-3Relevant articles and documents
Novel adenosine A3 receptor modulators
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Page/Page column 19-20, (2008/06/13)
A class of novel antagonists for the adenosine A3 receptor are disclosed. These compounds are useful as therapeutic agents for a number of diseases and medical conditions that are mediated by the A3 receptor. The compounds of this in
New pyrrolo[2,1-f]purine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives as potent and selective human A3 adenosine receptor antagonists
Baraldi, Pier Giovanni,Preti, Delia,Tabrizi, Mojgan Aghazadeh,Fruttarolo, Francesca,Romagnoli, Romeo,Zaid, Naser Abdel,Moorman, Allan R.,Merighi, Stefania,Varani, Katia,Borea, Pier Andrea
, p. 4697 - 4701 (2007/10/03)
Compounds presenting an additional fused ring on the xanthine nucleus have been reported to exhibit antagonistic activity with various levels of affinity and selectivity toward the four adenosine receptors subtypes A1, A2A, A2B