86252-77-9

Upstream product

• 130931-86-1 (-)-(1S,4R)-4-acetamidocyclopent-2-enylmethanol 
• 108-24-7 acetic anhydride 
• 216481-84-4 (1S,4R)-N-acetyl-1-amino-4-(hydroxymethyl)-2-cyclopentene 
• 65942-42-9 N-((1R,4S)-4-Hydroxymethyl-cyclopent-2-enyl)-acetamide 
• 61865-62-1 cis-4-aminocyclopent-2-nene-1-carboxylic acid hydrochloride 
• 77745-26-7 Methyl trans-4-Aminocyclopent-2-enecarboxylate Hydrochloride 
• 77745-25-6 cis-4-amino-2-cyclopentenecarboxylic acid methyl ester hydrochloride 
• 77745-28-9 cis-4-Aminocyclopent-2-enemethanol Hydrochloride 
• 205055-80-7 (1R,4S)-4-Acetylamino-cyclopent-2-enecarboxylic acid 
• 134003-04-6 (1R,4S)-4-aminocyclopenten-2-ene-1-carboxylic acid 
• 69919-17-1 methyl (+)-(1R,4S)-4-acetamido-cyclopent-2-ene carboxylate 
• 136522-35-5 (1R,4S)-1-amino-4-hydroxymethyl-2-cyclopentene 
• 1309768-09-9 (1S,4R)-methyl 4-azidocyclopent-2-enecarboxylate 
• 49805-30-3 2-azabicyclo[2.2.1.]hept-5-en-3-one 

Downstream Products

• 118353-05-2 (+/-)-cis-2-amino-1,9-dihydro-9-[4-(hydroxymethyl)-2-cyclopenten-1-yl]-6H-purin-6-one 
• 118237-87-9 cis-(+/-)-2-Amino-6-chloro-9-<4-(hydroxymethyl)-2-cyclopenten-1-yl>-9H-purine 
• 123288-54-0 3-aminocyclopentyl-1-methanol 

Relevant academic research and scientific papers

Acetoxy Meldrum's acid: A versatile acyl anion equivalent in the Pd-catalyzed asymmetric allylic alkylation

Acetoxy Meldrum's acid can serve as a versatile acyl anion equivalent in the Pd-catalyzed asymmetric allylic alkylation. The reaction of this nucleophile with various meso and racemic electrophiles afforded alkylated products in high yields and enantiopur

Deamination of cyclaradine by adenosine deaminase under high pressure

The deamination of cyclaradine corresponding to a carbocyclic analogue of ara-A having anti-HSV activity by adenosine deaminase was examined under various pressure. The deamination of (+)- and (±)-cyclaradine was remarkably facilitated by high pressure, and the rate was increased with increasing of pressure. However, (-)-cyclaradine was not deaminated even under high pressure.

Biocatalytical Transformations- VI. The 4-Acetamido-cyclopent-2-ene Carboxylate Route Revisited: Synthesis of (+)- and (-)-Aristeromycin

Enantiomerically pure (+)-as well as (-)-aristeromycin can be synthesized starting from (+)- or (-)-butyl (or hexyl) 4-acetamido-cyclopent-2-ene carboxylate; these carboxylates are easily obtained from their corresponding racemates by hydrolysis with the lipase from Candida rugosa.

Carbocyclic Sugar Amines: Synthesis and Stereochemistry of Racemic α- and β-Carbocyclic Ribofuranosylamine, Carbocyclic Lyxofuranosylamine, and Related Compounds

The facile and stereoselective synthesis of racemic carbocyclic β-ribofuranosylamine, carbocyclic β-lyxofuranosylamine, and related 2,3-cis-dihydroxy carbocyclic pentofuranosylamines is reported.In addition, the synthesis, isolation, and base-catalyzed epimerization of methyl cis-4-aminocyclopent-2-enecarboxylate are described.The epimerization at C(1) followed by stereoselective cis hydroxylation provides for the first time access to the racemic carbocyclic α-pentofuranosylamines.

Adenosine deaminase resistant antiviral purine nucleosides and method of preparation

The preparation of (±)-9-[α-(2α,3β-dihydroxy-4α-(hydroxymethyl) cyclopentyl)]-6-substituted purines: STR1 and (±)-3-[α-(2α, 3β-dihydroxy-4α-(hydroxymethyl)cyclopentyl)]-7-substituted-v-triazolo[4,5d]pyrimidines: STR2 and their derivatives wherein R is amino, mercapto, methylmercapto, hydroxy, halogen, or substituted amino: STR3 wherein R' and R" may be the same or different and are of hydrogen, methyl, ethyl, propyl or phenyl. The preparation of the single intermediate from which either of these series of compounds may be synthesized is also disclosed. The compounds exhibit antiviral and antitumor activity.