862675-34-1

Upstream product

• 109-04-6 2-bromo-pyridine 
• 1945-84-2 2-ethynylpyridine 
• 100-44-7 benzyl chloride 
• 100-70-9 2-Cyanopyridine 
• 622-79-7 benzyl azide 
• 100-39-0 benzyl bromide 
• 86521-05-3 2-(trimethylsilylethynyl)pyridine 
• 100-46-9 benzylamine 

Relevant academic research and scientific papers

Syntheses, structural characterization and photophysical properties of 4-(2-pyridyl)-1,2,3-triazole rhenium(i) complexes

Novel chelators, i.e., 4-(2-pyridyl)-1,2,3-triazole derivatives, were synthesized by means of Cu(i)-catalyzed 1,3-dipolar cycloaddition and used to prepare luminescent Re(i) complexes [ReCl(CO)3(Bn-pyta)], [ReCl(CO)3(AcGlc-pyta)] and

4,5-Di(2-pyridyl)-1,2,3-triazolate: The elusive member of a family of bridging ligands that facilitate strong metal-metal interactions

The new click-adduct 4,5-di(2-pyridyl)-1,2,3-triazole acts as a doubly-chelating anionic bridging ligand that forms dinuclear ruthenium(ii) complexes which exhibit strong metal-metal interactions. The Royal Society of Chemistry.

Selective Sensing of Phosphates by a New Bis-heteroleptic RuIIComplex through Halogen Bonding: A Superior Sensor over Its Hydrogen-Bonding Analogue

The selective phosphate-sensing property of a bis-heteroleptic RuIIcomplex, 1[PF6]2, which has a halogen-bonding iodotriazole unit, is demonstrated and is shown to be superior to its hydrogen-bonding analogue, 2[PF6]2. Complex 1[PF6]2, exploiting halogen-bonding interactions, shows enhanced phosphate recognition in both acetonitrile and aqueous acetonitrile compared with its hydrogen-bonding analogue, owing to considerable amplification of the RuII-center-based metal-to-ligand charge transfer (MLCT) emission response and luminescence lifetime. Detailed solution-state studies reveal a higher association constant, lower limit of detection, and greater change in lifetime for complex 1 in the presence of phosphates compared with its hydrogen-bonding analogue, complex 2. The1H NMR titration study with H2PO4?ascertains that the binding of H2PO4?occurs exclusively through halogen-bonding or hydrogen-bonding interactions in complexes 1[PF6]2and 2[PF6]2, respectively. Importantly, the single-crystal X-ray structure confirms the first ever report on metal-assisted second-sphere recognition of H2PO4?and H2P2O72?with 1 through a solitary C?I???anion halogen-bonding interaction.

Ru(II) coordination compounds of N[sbnd]N bidentate chelators with 1,2,3 triazole and isoquinoline subunits: Synthesis, spectroscopy and antimicrobial properties

Bidentate chelators 1-(1-benzyl-1,2,3-triazol-4-yl)isoquinoline and 3-(1-benzyl-1,2,3-triazol-4-yl)isoquinoline were prepared from benzyl bromide and trimethylsilylethynylisoquinoline precursors using a tandem deprotection/substitution/CuAAC synthetic approach. Each chelator is capable of forming a stable 3:1 Ru(II) coordination compound, which forms as a geometric isomer mixture. These Ru(II) complexes possess unique MLCT absorbance signatures at 450/472 nm (1-isomer) and 367 nm (3-isomer) relative to their constituent chelating units. Minimum inhibitory concentration values as low as 0.4 μM are observed for Ru(II) complexes against representative Gram-positive bacteria Bacillus subtilis and Staphylococcus epidermidis. Comparing the MIC values of these isoquinoline compounds with analogous 2-(1-benzyl-1,2,3-triazol-4-yl)pyridine compounds shows a 2.5- to 40-fold improvement in potency. This study establishes that increased hydrophobicity introduced at the central chelating units of Ru(II) coordination compounds can be a useful means by which to optimize antimicrobial activity that is complimentary to the variation of peripheral substituent identity at the chelator's N1 triazole position.

Click-triazole: Coordination of 2-(1,2,3-triazol-4-yl)-pyridine to cations of traditional tetrahedral geometry (Cu(i), Ag(i))

Coordination studies of the pyridine-triazole diad to copper(i) and silver(i) reveal the potential and conditions for the solution- and solid-state self-assembly of supramolecular architectures based on this motif.

Side-Arm Functionalized Silylene Copper(I) Complexes in Catalysis

A convenient new method was added to the toolbox of the ligand design of N-heterocyclic silylenes and their transition-metal complexes. Herein we report on six novel compounds of two novel classes of copper(I) complexes based on the benzamidinate silylene

Ru-TAP complexes with btz and pytz ligands: Novel candidates as photooxidizing agents

Two ligands containing 1,2,3-triazole moieties 1 and 3 were easily prepared by a CuI-catalysed "click reaction" between commercially available (trimethylsilyl)alkynes and benzyl azide. These ligands were used in the synthesis of Ru(II) complexes with TAP ligands, i.e. [Ru(TAP) 2btz]2+2 and [Ru(TAP)2pytz]2+4. The electrochemical and photophysical properties of these complexes were investigated. The data show that both complexes should behave as highly oxidizing agents under illumination. However, complex 4 displays more attractive photophysical properties than complex 2 and constitutes thus a Ru-TAP compound that can be easily derivatized for photodamaging biomolecules.

Copper immobilized on biomimetic assembled calcium carbonate/carboxymethylcellulose hybrid: a highly active recoverable catalyst for CuAAC reactions

A novel copper immobilized on biomimetic assembled carboxymethylcellulose/calcium carbonate hybrid (CuII@CMC/CaCO3) as an efficient heterogeneous catalyst for the synthesis of 1,2,3-triazoles has been described herein. The fabrication of CuII@CMC/CaCO3 is accomplished through a bioinspired mineralization process using sodium carboxymethylcellulose (CMC-Na) as the template and ion exchange agent, while the metathesis, nucleation, assemble, hybridization, and immobilization of Cu(II) occurred by successful treatment with CaCl2, Na2CO3, and CuSO4 in water at room temperature. The resultant CuII@CMC/CaCO3 hybrid was well characterized by various analyses such as FT-IR, XRD, SEM, EDX, EDX-mapping, TEM, and TGA techniques. In the presence of low copper loading of CuII@CMC/CaCO3 hybrid, benzylic halides, azide, and alkynes proceeded smoothly to afford 1,4-disubstituted 1,2,3-triazoles in high yields. The catalyst can be conveniently recovered from the reaction mixture by filter and reused for at least 5 consecutive runs with a slight drop in its catalytic activity. The remarkable activity and stability of the catalyst may be attributed to the coordination of both carboxyl and hydroxyl groups of the hybrid of CMC/CaCO3.

Rhenium Complexes of Pyridyl-Mesoionic Carbenes: Photochemical Properties and Electrocatalytic CO2 Reduction

Mesoionic carbenes have found wide use as components of homogeneous catalysts. Recent discoveries have, however, shown that metal complexes of such ligands also have huge potential in photochemical research and in the activation of small molecules. We pre

Dinuclear Cu(I) Halides with Terphenyl Phosphines: Synthesis, Photophysical Studies, and Catalytic Applications in CuAAC Reactions

Several dinuclear terphenyl phosphine copper(I) halide complexes of composition [CuX(PR2Ar′)]2 (X = Cl, Br, I; R = hydrocarbyl, Ar′ = 2,6-diarylterphenyl radical), 1-5, have been isolated from the reaction of CuX with 1 equiv of the phosphine ligand. Most