862899-96-5Relevant academic research and scientific papers
Oxazolium Salts as Organocatalysts for the Umpolung of Aldehydes
Garapati, Venkata Krishna Rao,Gravel, Michel
, p. 6372 - 6375 (2018)
Oxazolium salts were successfully employed for the first time as organocatalysts for benzoin, Stetter, and redox esterification reactions. An N-mesityl oxazolium salt catalyzed homobenzoin reaction of aromatic, heteroaromatic, and aliphatic aldehydes delivered α-hydroxy ketones in high yields. This new type of catalyst proved remarkably effective for the Stetter reaction of challenging substrates such as β-alkyl-α,β-unsaturated ketones and electron-rich aromatic aldehydes in comparison to common thiazolium and triazolium salts.
Synthesis method of oxazole type n-heterocyclic carbene precursor
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Paragraph 0019-0027, (2019/11/12)
The invention discloses a synthesis method of an oxazole type n-heterocyclic carbene precursor. The synthesis method includes the steps that oxazole A and a benzyl halide compound B are dissolved in an organic solvent for stirring reaction at 80-120 DEG C
