86340-81-0Relevant academic research and scientific papers
Mg0-promoted selective C-F bond cleavage of trifluoromethyl ketones: A convenient method for the synthesis of 2,2-difluoro enol silanes
Amii, Hideki,Kobayashi, Takeshi,Hatamoto, Yasushi,Uneyama, Kenji
, p. 1323 - 1324 (2007/10/03)
2,2-difluoro enol silyl ethers were readily prepared by Mg0 promoted selective defluorination of trifluoromethyl ketones in the presence of TMSCI, which involves C-F bond cleavage.
An efficient and general method for the reformatsky-type reaction of chlorodifluoromethyl ketones with carbonyl compounds giving α,α-difluoro-β-hydroxy ketones1)
Kuroboshi,Ishihara
, p. 428 - 437 (2007/10/02)
Chlorodifluoromethyl ketones CF2ClCOR, where R is an alkyl, aryl, and l-alkynyl group, underwent the Reformatsky-type aldol reaction with a wide variety of aldehydes or ketones in the presence of acid-washed zinc dust and copper(I) chloride or
ZINC-COPPER(I) CHLORIDE OR -SILVER(I) ACETATE PROMOTED ALDOL REACTION OF CHLORODIFLUOROMETHYL KETONES WITH CARBONYL COMPOUNDS. A GENERAL AND EFFECTIVE ROUTE TO α,α-DIFLUORO-β-HYDROXY KETONES
Kuroboshi, Manabu,Ishihara, Takashi
, p. 6481 - 6484 (2007/10/02)
Chlorodifluoromethyl ketones efficiently underwent the aldol reaction with a variety of aldehydes or ketones in the presence of zinc, a catalytic amount of copper(I) chloride or silver(I) acetate, and molecular sieves to give the corresponding α,α-difluor
A CONVENIENT SYNTHESIS OF 2,2-DIFLUORO ENOL SILYL ETHERS FROM CHLORODIFLUOROMETHYL KETONES
Yamana, Masayuki,Ishihara, Takashi,Ando, Teiichi
, p. 507 - 510 (2007/10/02)
Various chlorodifluoromethyl ketones can be converted to the corresponding 2,2-difluoro enol silyl ethers in good yields, by the action of zinc dust and chlorotrimethylsilane in dry acetonitrile at 60 degC.
