863408-46-2

Upstream product

• 863408-41-7 N⁶-acetyl-5′-O-(4,4′-dimethoxytrityl)-2′-O-(2-cyannethoxymethyl)adenosine 
• 124482-92-4 2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine 
• 16265-37-5 N₆-acetyl-adenosine 
• 231957-26-9 N⁶-acetyl-5'-O-(4,4'-dimethoxytrityl)adenosine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 

Relevant academic research and scientific papers

A new RNA synthetic method with a 2′-O-(2-cyanoethoxymethyl) protecting group

(Chemical Equation Presented) A novel method for the synthesis of RNA oligomers with 2-cyanoethoxymethyl (CEM) as the 2′-hydroxyl protecting group has been developed. The new method allows the synthesis of oligoribonucleotides with an efficiency and final

METHOD FOR DETACHING PROTECTING GROUP ON NUCLEIC ACID

A method is provided for removing a 2-cyanoethoxymethyl (CEM) group and substituting the 2′-hydroxyl group of each ribose of an oligonucleic acid derivative with good reproducibility and high efficiency.

METHOD FOR REMOVAL OF NUCLEIC ACID-PROTECTING GROUP

The main object of the present invention is to provide a method for efficiently removing the silicon substituent which protects the 3'-hydroxyl group and the 5'-hydroxyl group of a ribose of a ribonucleic acid derivative in which the 2'-hydroxyl group of

PHOSPHORAMIDITE COMPOUND AND METHOD FOR PRODUCING OLIGO-RNA

An object of the present invention is to provide a useful and novel phosphoramidite compound for the synthesis of oligo-RNA. A phosphoramidite compound represented by the following general formula (1), wherein: Bx represents a nucleobase which