A new RNA synthetic method with a 2′-O-(2-cyanoethoxymethyl) protecting group

DOI: 10.1021/ol051151f

Source and publish data:

Organic Letters p. 3477 - 3480 (2005)

Update date:2022-07-30

Topics:

Authors:

Ohgi, Tadaaki

Masutomi, Yutaka

Ishiyama, Kouichi

Kitagawa, Hidetoshi

Shiba, Yoshinobu

Yano, Junichi

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Article abstract of DOI:10.1021/ol051151f

(Chemical Equation Presented) A novel method for the synthesis of RNA oligomers with 2-cyanoethoxymethyl (CEM) as the 2′-hydroxyl protecting group has been developed. The new method allows the synthesis of oligoribonucleotides with an efficiency and final

Full text of DOI:10.1021/ol051151f

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