863498-08-2

Upstream product

• 863498-07-1 1-benzenesulfonyl-2-[2-(2-nitro-phenyl)-vinyl]-1H-indole 
• 4885-02-3 Dichloromethyl methyl ether 
• 23308-83-0 (2-nitrobenzyl)triphenylphosphonium bromide 
• 80360-23-2 1-(phenylsulfonyl)-1H-indole-2-carbaldehyde 

Downstream Products

• 863498-10-6 1-benzenesulfonyl-3-(1-methoxymethoxy-prop-2-ynyl)-2-[2-(2-nitro-phenyl)-vinyl]-1H-indole 
• 863498-09-3 1-{1-benzenesulfonyl-2-[2-(2-nitro-phenyl)-vinyl]-1H-indol-3-yl}-prop-2-yn-1-ol 

Relevant academic research and scientific papers

Synthesis of N-protected indolaldehydes using modified Hass procedure

A detailed study on oxidation of N-protected bromomethylindoles into the respective aldehydes was carried out. Using a modified Hass procedure, synthesis of aryl-/hetero-aryl aldehydes in particular indolaldehydes is achieved in reasonable yields.

A new total synthesis of an indolo[3,2-j]phenanthridine alkaloid calothrixin B

A new total synthesis of calothrixin B is described. The key step is an allene-mediated electrocyclic reaction involving the indole 2,3-bond for the construction of a suitable 4-oxygenated 2,3,4-trisubstituted carbazole ring system.