863886-52-6Relevant articles and documents
Synthesis of 1-(4-((E)-3-arylacryloyl) phenyl)-3,4-dibromo-1Hpyrrole-2,5- diones and screening for anti-Candida and antituberculosis activity
Patel, J. R.,Dholakiya, B. Z.
, p. 1977 - 1983,7 (2020/07/30)
A series of eleven 1-(4-((E)-3-arylacryloyl) phenyl)-3,4 dibromo-1H-pyrrole-2,5-diones (4′-aminochalcone- based dibromomaleimides) were synthesized using maleic anhydride and p-aminoacetophenone as starting material. Furthermore, there has been some additional work investigating the effect of these derivatives on biological activity. They were characterized using FTIR, 1H NMR, 13C NMR, ESI mass spectroscopy, and elemental analysis. The compounds show anti-Candida & antituberculosis activity.