1332864-07-9Relevant academic research and scientific papers
Synthesis of 1-(4-((E)-3-arylacryloyl) phenyl)-3,4-dibromo-1Hpyrrole-2,5- diones and screening for anti-Candida and antituberculosis activity
Patel, J. R.,Dholakiya, B. Z.
, p. 1977 - 1983,7 (2020/07/30)
A series of eleven 1-(4-((E)-3-arylacryloyl) phenyl)-3,4 dibromo-1H-pyrrole-2,5-diones (4′-aminochalcone- based dibromomaleimides) were synthesized using maleic anhydride and p-aminoacetophenone as starting material. Furthermore, there has been some additional work investigating the effect of these derivatives on biological activity. They were characterized using FTIR, 1H NMR, 13C NMR, ESI mass spectroscopy, and elemental analysis. The compounds show anti-Candida & antituberculosis activity.
Silica sulfuric acid-catalyzed Claisen-Schmidt condensation of 1,3,4 trisubstituted pyrrole 2,5 dione to chalcones
Patel,Malani,Dholakiya
, p. 2371 - 2381 (2013/02/25)
A series of 11 chalcones was synthesized from 1-(4-acetylphenyl)-3,4- dibromo-1H-pyrrole-2,5-dione with various substituted benzaldehyde under solvent-free conditions using silica-sulphuric acid as a catalyst. The yields of chalcones are more than 90 %. All the compounds were characterized by physical, spectroscopic, and elemental analysis. Springer Science+Business Media B.V. 2012.
