864066-74-0

Basic information

• Product Name: RAFT polymerization agent
• Synonyms: 4-Cyano-4-(phenylcarbonothioylthio)pentanoic acid N-hydroxysuccinimide ester;4-Cyano-4-(phenylcarbonothioylthio)pentanoic acid N-succinimidyl ester;4-Cyano-4-[(phenylthioxomethyl)thio]-2,5-dioxo-1-pyrrolidinyl ester pentanoic acid;NHS protected RAFT;RAFT polymerization agent
• CAS NO: 864066-74-0
• Molecular Formula: C₁₇H₁₆N₂O₄S₂
• Molecular Weight: 376.45
• Mol File: 864066-74-0.mol
• Article Data: 10

Chemical Properties

• Melting Point: 175-185°C
• Boiling Point: 538.9±60.0 °C(Predicted)
• Appearance: /
• Density: 1.40±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: RAFT polymerization agent(CAS DataBase Reference)
• NIST Chemistry Reference: RAFT polymerization agent(864066-74-0)
• EPA Substance Registry System: RAFT polymerization agent(864066-74-0)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 864066-74-0(Hazardous Substances Data)

Usage

Uses

Reversible Addition Fragmentation Chain Transfer (RAFT) Polymerization.RAFT agent for controlled radical polymerization; This is the NHS protected version of 722995; well suited for methacrylates and methacrylamides; Chain Transfer Agent (CTA)

General Description

Need help choosing the correct RAFT Agent? Please consult the RAFT Agent to Monomer compatibility table.

Upstream product

• 2638-94-0 4,4'-dicyano-4,4'-azo-di-valeric acid 
• 121-68-6 dithiobenzoic acid 
• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 201611-92-9 4-cyano-4-(thiobenzoylthio)pentanoic acid 

Downstream Products

• 864066-75-1 C₁₄₄H₁₈₄N₂₂O₈S₁₆ 

Relevant articles and documents

Fabrication of Reductive-Responsive Prodrug Nanoparticles with Superior Structural Stability by Polymerization-Induced Self-Assembly and Functional Nanoscopic Platform for Drug Delivery

A highly efficient strategy, polymerization-induced self-assembly (PISA) for fabrication of the polymeric drug delivery systems in cancer chemotherapy is reported. Diblock prodrug copolymer, PEG-b-P(MEO2MA-co-CPTM) was used as the macro-RAFT ag

Synthesis of cationic N-[3-(dimethylamino)propyl]methacrylamide brushes on silicon wafer via surface-initiated RAFT polymerization

Surface-initiated reversible addition-fragmentation chain transfer (SI-RAFT) polymerization of N-[3-(dimethylamino)propyl]methacrylamide (DMAPMA) on the silicon wafer was conducted in attempt to create controllable cationic polymer films. The RAFT agent-i

ANTIBODY-POLYMER-CONJUGATES

The present invention relates to antibody-polymer conjugates which have high drug carrying capacity and which can realize active targeting thanks to the antibody existing thereon.

A switchable polymer brush system for antifouling and controlled detection

A stimuli-responsive polymer brush system is designed to switch on and off surface functionality and prevent functional groups from fouling by grafting together two polymer brushes with precisely controlled lengths. The polymer brush with functional group