86423-53-2Relevant academic research and scientific papers
Two-carbon homologation of Grignard reagents to primary amines
Osowska-Pacewicka, Krystyna,Zwierzak, Andrzej
, p. 333 - 335 (2007/10/03)
A novel, convenient synthesis of N-(diethoxyphosphoryl)aziridine is described. Application of this compound as a synthetic equivalent of an a2 type synthon for aminoethylation of Grignard reagents is demonstrated.
Novel organophosphorus reagents for the synthesis of amines
Zwierzak, Andrzej,Osowska-Pacewicka, Krystyna
, p. 569 - 572 (2007/10/03)
New organophosphorus equivalents of a2 type N-protected amine synthons are presented.
PO-Activated Olefination and Conversion of Aldehydes and Ketones to Higher Amines; II. Synthesis of Arylethylamines
Heymes, A.,Chekroun, I.
, p. 245 - 249 (2007/10/02)
The transformation of arylcarboxaldehydes and/or - ketones 2 by three different routes into arylethylamines 3 and/or 4 is reported.According to the first route, the intermediate iminophosphonates 9 react through a classical PO-activated olefination.The second and the third involve the rearrangement of the iminophosphonates 9 into the vinylphosphoramidates 12.
