864296-75-3

Upstream product

• 4668-41-1 N₂-benzyloxycarbonyl-l-glutamine ethyl ester 
• 2650-64-8 Cbz-L-Gln 
• 64-17-5 ethanol 
• 15231-21-7 (S)-2-((phenylmethoxycarbonyl)amino)-4-cyanobutanoic acid 

Downstream Products

• 1323371-12-5 C₂₃H₂₄N₄O₆ 
• 1323371-16-9 5-benzyloxycarbonylimino-1-methyl-L-proline amide 
• 1323371-11-4 (S)-6-amino-3-[(benzyloxycarbonyl)(methyl)amino]-2,3,4,5-tetrahydropyridin-2-one 
• 1323371-10-3 ethyl (S)-2-[(benzyloxycarbonyl)(methyl)amino]-4-cyanobutanoate 
• 864296-76-4 (2S)-2-(benzyloxycarbonyl-amino)-4-(1H-tetrazol-5-yl)-butyric acid ethyl ester 

Relevant academic research and scientific papers

A novel rearrangement of cyclic glutamine derivatives: Ring contraction in 3,6-diamino-2,3,4,5-tetrahydropyridin-2-ones to yield 5-iminoproline amides

A new rearrangement of the cyclic L-glutamine derivative(S)-6- carbamoylamino-3-(methylamino)-2,3,4,5-tetrahydropyridin-2-one (2) and its descarbamoyl analogue 10-H was found to yield enantiomerically pure 5-carbamoylimino-1-methyl-L-proline amide (12-CON

New carboxylic acid amides, the preparation thereof and their use as medicaments

The present invention relates to new substituted carboxylic acid amides of general formula wherein A, B and R1 to R5 are defined as in claim 1, the tautomers, the enantiomers, the diastereomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable properties.

NOVEL CARBOXAMIDES FOR USE AS XA INHIBITORS

The invention relates to the novel substituted carboxamides of general formula (I), wherein A, B and R1 to R5 are defined as in claim 1, the tautomers, enantiomers, diastereomers, mixtures and salts thereof, especially the physiologically salts thereof with inorganic or organic acids or bases, which have valuable properties. The inventive compounds have an antithrombotic effect and are factor Xa inhibitors.