4668-41-1

Upstream product

• 2650-64-8 Cbz-L-Gln 
• 75-03-6 ethyl iodide 
• 501-53-1 benzyl chloroformate 
• 56-85-9 L-glutamine 
• 64-17-5 ethanol 
• 50516-14-8 Nα-benzyloxycarbonyl-glutamine 

Downstream Products

• 5672-81-1 (4S)-4-{[(benzyloxy)carbonyl]amino}-5-ethoxy-5-oxopentanoic acid 
• 864296-75-3 (S)-2-(benzyloxycarbonylamino)-4-cyanobutanoate 
• 1064033-40-4 (S)-ethyl 2-(benzyloxycarbonylamino)-5-((S)-1-ethoxy-3-hydroxy-1-oxopropan-2-ylamino)-5-oxopentanoate 
• 1323371-11-4 (S)-6-amino-3-[(benzyloxycarbonyl)(methyl)amino]-2,3,4,5-tetrahydropyridin-2-one 
• 1323371-16-9 5-benzyloxycarbonylimino-1-methyl-L-proline amide 
• 1323371-12-5 C₂₃H₂₄N₄O₆ 

Relevant academic research and scientific papers

COMPOSITIONS AND METHODS FOR PROTECTING CELLS FROM TOXIC EXPOSURES

The present invention provides compositions and methods for protecting cells and tissues from damage associated with therapeutic treatments of cancers and other diseases and conditions where reactive oxygen species are produced. The present invention also

Papain-catalyzed esterification of N(α)-protected amino acids and dipeptides with ethanol in different organic systems

The papain-catalyzed esterification of N(α)-protected amino acids and dipeptides with ethanol in mostly hydrophobic organic solvent systems containing low amounts of water has been investigated. The influence of various parameters, such as the amount of added water, reaction time, temperature and pH of added buffer, on the yield of ester was studied first on the model substrate Z-Ala. The optimized reaction conditions were then used for esterification of a series of N(α)-protected amino acids and dipeptides.

PAPAIN-ASSISTED RESOLUTION OF NATURAL AND XENOBIOTIC α-AMINO ACIDS

A new and convenient method for the preparation of pure enantiomers of α-amino acids is described.Industrial papain, catalyzes the synthesis of L-Z-amino acid ethyl esters in ethanolic medium, with good yields.These esters are obtained from DL-Z-amino acids with 100percent optical purity.Unreactive D-Z-amino acids are readily isolated from reaction medium.Physical constants of natural and xenobiotic L-Z-amino acid esters and D-Z-amino acids are described.