864514-27-2

Upstream product

• 864514-26-1 Acetic acid (4R,6R)-4-(tert-butyl-dimethyl-silanyloxy)-5,5-dimethyl-6-(2-oxo-ethyl)-tetrahydro-pyran-2-yl ester 
• 50625-55-3 5-methyl-2,4-dimethoxy-benzoic acid 
• 864514-42-1 Acetic acid (4R,6R)-4-(tert-butyl-dimethyl-silanyloxy)-6-(2-hydroxy-butyl)-5,5-dimethyl-tetrahydro-pyran-2-yl ester 
• 864514-17-0 4,6-bis-(4-methoxy-benzyloxy)-3-methyl-2-(2-oxo-ethyl)-benzoic acid methyl ester 
• 38064-90-3 2,4-dimethoxytoluene 
• 7149-91-9 2,4-dimethoxy-5-methyl-benzaldehyde 
• 864514-37-4 N,N-diethyl-2,4-dimethoxy-5-methyl-benzamide 
• 864514-41-0 [(2R,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-hydroxy-3,3-dimethyl-tetrahydro-pyran-2-yl]-acetaldehyde 
• 864514-24-9 (4R,6R)-5,5-dimethylnona-1,8-diene-4,6-diol 
• 126-30-7 2,2-Dimethyl-1,3-propanediol 
• 864514-40-9 2-allyl-4,6-bis-(4-methoxy-benzyloxy)-3-methyl-benzoic acid methyl ester 
• 864514-39-6 methyl 2-allyl-4,6-dihydroxy-3-methylbenzoate 
• 864514-38-5 2-allyl-N,N-diethyl-4,6-dihydroxy-3-methyl-benzamide 
• 864514-21-6 2-allyl-N,N-diethyl-4,6-dimethoxy-3-methyl-benzamide 

Downstream Products

• 1402588-79-7 C₅₀H₇₃NO₉Si₂ 
• 1402588-80-0 C₅₀H₇₅NO₁₀Si₂ 
• 1402588-81-1 C₄₂H₆₇NO₉Si₂ 
• 1402588-83-3 C₄₁H₆₃NO₉Si₂ 
• 1402588-84-4 C₅₁H₈₃NO₁₂Si₂ 
• 1402589-26-7 C₅₁H₈₃NO₁₂Si₂ 
• 1402588-85-5 C₅₈H₈₇NO₁₃Si₂ 
• 1402588-86-6 C₅₀H₇₉NO₁₂Si₂ 
• 864514-28-3 (2S,4R,6R)-6-{(2S,3R)-3-[(R)-6,8-Bis-(4-methoxy-benzyloxy)-5-methyl-1-oxo-isochroman-3-yl]-2-hydroxy-butyl}-4-(tert-butyl-dimethyl-silanyloxy)-5,5-dimethyl-tetrahydro-pyran-2-carbonitrile 
• 864514-30-7 (2S,4R,6R)-6-{(2S,3R)-3-[(R)-6,8-Bis-(4-methoxy-benzyloxy)-5-methyl-1-oxo-isochroman-3-yl]-2-hydroxy-butyl}-4-hydroxy-5,5-dimethyl-tetrahydro-pyran-2-carboxylic acid amide 
• 864514-29-4 (2S,4R,6R)-6-{(2S,3R)-3-[(R)-6,8-Bis-(4-methoxy-benzyloxy)-5-methyl-1-oxo-isochroman-3-yl]-2-hydroxy-butyl}-4-hydroxy-5,5-dimethyl-tetrahydro-pyran-2-carbonitrile 

Relevant academic research and scientific papers

Studies toward the unique pederin family member psymberin: Full structure elucidation, two alternative total syntheses, and analogs

Two synthetic approaches to psymberin have been accomplished. A highly convergent first generation synthesis led to the complete stereochemical assignment and demonstrated that psymberin and irciniastatin A are identical compounds. This synthesis featured

Synthesis and complete stereochemical assignment of psymberin/irciniastatin for use as antitumor compounds

The invention relates to the synthesis and complete stereochemical assignments of cytotoxic compounds such as compound 28-a and its stereoisomers: The invention further provides processes for making the compounds, their synthetic intermediates, and for me

Synthesis and complete stereochemical assignment of psymberin/irciniastatin A

We describe a concise and flexible synthetic avenue for the preparation of compounds with structures relevant to those proposed for the novel marine-derived differential cytotoxins psymberin and irciniastatin A. Our efforts led to their complete stereoche