86456-56-6

Usage

Uses

Used in Pharmaceutical Industry:
6-Bromonaphthalene-1-carboxaldehyde is used as an intermediate in the synthesis of pharmaceuticals, contributing to the development of new drugs and medications.
Used in Agrochemical Industry:
6-Bromonaphthalene-1-carboxaldehyde, is also utilized as an intermediate in the production of agrochemicals, which are essential for agricultural applications to protect crops and enhance yields.
Used in Dye Industry:
6-Bromonaphthalene-1-carboxaldehyde is employed in the synthesis of dyes, which are used in various industries such as textiles, plastics, and printing.
Used in Perfume and Fragrance Industry:
This chemical is used in the manufacturing of perfumes and fragrances, providing unique scents and enhancing the sensory experience of consumers.
Used in Organic Chemical Production:
6-Bromonaphthalene-1-carboxaldehyde is also utilized in the production of other organic chemicals, expanding its applications across various chemical industries.
It is crucial to handle and store 6-Bromonaphthalene-1-carboxaldehyde with care due to its potential health risks if not properly managed.

Upstream product

• 66-77-3 1-naphthaldehyde 
• 51934-38-4 6-bromo-1-naphthoic acid 
• 177846-05-8 6-bromo-1,2-dihydronaphthalene-1-carboxylic acid 
• 14062-25-0 Ethyl 4-bromophenylacetate 
• 177846-03-6 6-Bromo-4-hydroxy-1,2,3,4-tetrahydro-naphthalene-1-carboxylic acid 
• 86456-65-7 Methanesulfonic acid 3-(4-bromo-phenyl)-butyl ester 
• 86456-67-9 7-bromo-1-hydroxy-4-methyl-1,2,3,4-tetrahydronaphthalene 
• 86456-66-8 4-(4-bromophenyl)pentanenitrile 
• 86456-68-0 6-bromo-1-methylnaphthalene 
• 31042-07-6 4-(4-bromophenyl)pentanoic acid 
• 51644-34-9 7-bromo-4-methyl-1,2,3,4-tetrahydro-1H-naphthalen-1-one 
• 53086-46-7 3-(4-bromophenyl)butanoic acid 
• 159755-11-0 1-bromo-4-(1-bromoethyl)benzene 
• 20005-55-4 3-(4-bromophenyl)-1-butanol 

Downstream Products

• 86456-62-4 o-<(6-bromo-1-naphthyl)methyl>acetophenone 
• 86456-60-2 o-<(6-bromo-1-naphthyl)methyl>benzoic acid 
• 86456-72-6 2-(6-Bromo-naphthalen-1-ylmethyl)-benzoyl chloride 

Relevant academic research and scientific papers

PD-1/PD-L1 INHIBITORS

Compounds according to formula (I), methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.

Concise Synthesis of Natural Phenylphenalenone Phytoalexins and a Regioisomer

Concise total syntheses of the natural phytoalexins 2-hydroxy-8-(4-hydroxyphenyl)phenalen-1-one (1), 2-hydroxy-8-(3,4-dihydroxyphenyl)phenalen-1-one (2), and hydroxyanigorufone (4), together with regioisomer 3 are accomplished in 11 or 12 steps. The synthetic strategy features a Friedel-Crafts acylation to construct the 1H-phenalen-1-one tricyclic core followed by a Suzuki cross-coupling to obtain the target compounds.

Heterocyclic derivatives for the treatment of cancer and other proliferative diseases

The invention relates to certain heterocyclic compounds useful for the treatment of cancer and other diseases, having the Formula (I): wherein: (a) m is an integer 0 or 1; (b) R12 is an alkyl, a substituted alkyl, a cycloalkyl, a substituted cycloalkyl, a heterocyclic, a substituted heterocyclic, a heteroaryl, a substituted heteroaryl, an aryl or a substituted aryl residue; (c) Ar3 is an aryl, a substituted aryl, a heteroaryl or a substituted heteroaryl residue; (d) Ar4 is an aryl, a substituted aryl, a heteroaryl or a substituted heteroaryl residue; (e) R5 is hydrogen, hydroxy, alkyl or substituted alkyl; (f) - - - - - represents a bond present or absent; and (g) W, X, Y and Z are independently or together C(O)—, C(S), S, O, or NH; or a pharmaceutically acceptable salt thereof.