864667-17-4Relevant articles and documents
Selective bifunctionalization of pyrido[2,3-d]pyrimidines in positions 2 and 4 by SNAr and palladium-catalyzed coupling reactions
Lavecchia,Berteina-Raboin,Guillaumet
, p. 5851 - 5855 (2007/10/03)
Selective disubstitution of 2,4-dichloropyrido[2,3-d]pyrimidine with various nucleophiles was investigated. Suzuki and Stille cross-coupling reactions on monosubstituted compound 4-tert-butylamino-2-chloro-pyrido[2,3-d] pyrimidine were performed in high yields.