86475-58-3

Upstream product

• 532-20-7 D-(-)-ribose 
• 217309-46-1 5-(tert-butyldimethylsilyloxy)-2,3-isopropylidenedioxy-D-ribofuranose 
• 67814-68-0 2,3-O-isopropylidene-D-ribofuranose 
• 75921-20-9 5-O-<(1,1-dimethylethyl)dimethylsilyl>-2,3-O-(1-methylethylidene)-β-D-ribofuranose 
• 5707-04-0 Phenylselenyl chloride 
• 86468-17-9 (E)-Ethyl (4S,5R,6R)-7-Dimethyl-t-butylsiloxy-6-hydroxy-4,5-O-isopropylidene-2-methylhept-2-enoate 
• 86468-17-9 ethyl (4S,5R,6R)-7-t-butyldimethylsilyloxy-6-hydroxy-4,5-O-isopropylidene-2-methylhept-2-enoate 

Relevant academic research and scientific papers

Preparation of Key Intermediates for the Synthesis of C-Nucleosides and other Derivatives of 1-Deoxyribose

The reaction of D-ribose with stabilised ylides can be made to yield solely acyclic products, which may then be cyclised with high stereoselectivity using phenylselenenyl chloride to produce 1-β-substituted 1-deoxyribose derivatives.

The Preparation and Utility of Ethyl 2-(5'-O-t-Butyldimethylsilyl-2',3'-O-isopropylidene-β-D-ribofuranosyl)propenoate as a Key Intermediate for C-Nucleoside Synthesis

We described a short route from D-ribose to compounds (Ib) and (Ic), which can be converted into the showdomycin derivative (IIb) and certain novel C-nucleosides.A key step in this synthetic sequence involved a stereoselective cyclisation facilitated by t