86483-54-7

Basic information

• Product Name: 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
• Synonyms: 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER;3-Quinolinecarboxylic acid, 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, ethyl ester
• CAS NO: 86483-54-7
• Molecular Formula: C₁₅H₁₃ClFNO₃
• Molecular Weight: 309.7200232
• Mol File: 86483-54-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER(86483-54-7)
• EPA Substance Registry System: 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER(86483-54-7)

Safety Data

• Hazardous Substances Data: 86483-54-7(Hazardous Substances Data)

Usage

Uses

Ethyl 7-Chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylate is a quinolone derivative that has been studied as a reagent in the preparation of anti-HIV agents

Upstream product

• 16173-58-3 N,N-dimethylaminoacrylic acid ethyl ester 
• 37026-85-0 tri-n-butylammonium bromide 
• 86393-34-2 2,4-dichloro-5-fluorobenzoyl chloride 
• 765-30-0 Cyclopropylamine 

Downstream Products

• 93107-08-5 ciprofloxacin hydrochloride 
• 1412409-69-8 ethyl 1-cyclopropyl-7-((2S,2'S,5R,5'R)-5,5'-dibenzyl-2,2'-bimorpholino)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate 
• 1375100-76-7 3-((4-nitrobenzylidene)hydrazinecarbonyl)-7-(N'-(4-nitrobenzylidene)hydrazino)-1-cycloproyl-6-fluoroquinolin-4(1H)-one 
• 1375100-75-6 3-((4-fluorobenzylidene)hydrazinocarbonyl)-7-(N'-(4-fluorobenzylidene)hydrazino)-1-cycloproyl-6-fluoroquinolin-4(1H)-one 
• 1375100-74-5 3-((3-hydroxy-4-methoxybenzylidene)hydrazinocarbonyl)-7-(N'-(3-hydroxy-4-methoxybenzylidene)hydrazino)-1-cycloproyl-6-fluoroquinolin-4(1H)-one 
• 1375100-73-4 3-((3,4,5-trimethoxybenzylidene)hydrazinocarbonyl)-7-(N'-(3,4,5-trimethoxybenzylidene)hydrazino)-1-cycloproyl-6-fluoroquinolin-4(1H)-one 
• 1375100-71-2 3-((4-methoxybenzylidene)hydrazinocarbonyl)-7-(N'-(4-methoxybenzylidene) hydrazino)-1-cycloproyl-6-fluoroquinolin-4(1H)-one 
• 1375100-70-1 3-((2-hydroxybenzylidene)hydrazinocarbonyl)-7-(N'-(2-hydroxybenzylidene)hydrazino)-1-cycloproyl-6-fluoroquinolin-4(1H)-one 
• 1375100-69-8 3-(benzylidenehydrazinocarbonyl)-7-(N'-benzylidenehydrazino)-1-cycloproyl-6-fluoroquinolin-4(1H)-one 
• 93106-60-6 enrofloxacin 
• 85721-33-1 ciprofloxacin 
• 86393-33-1 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid 

Relevant articles and documents

Process for preparing quinolone- and naphthyridone- carboxylic acids and esters thereof

An improved process for preparing quinolone- and naphthyridonecarboxylic acids and esters thereof from benzoyl chlorides and nicotinoyl chlorides, respectively, in which the reaction carried out in the presence of a non-polar to slightly polar solvent without separation of intermediaries that form during the process.