864837-22-9Relevant articles and documents
Facile synthesis of 2′-O-cyanoethyluridine by ring-opening reaction of 2,2′-anhydrouridine with cyanoethyl trimethylsilyl ether in the presence of BF3·Et2O
Saneyoshi, Hisao,Okamoto, Itaru,Masaki, Yoshiaki,Ohkubo, Akihiro,Seio, Kohji,Sekine, Mitsuo
, p. 8554 - 8557 (2008/09/17)
In this Letter, a facile method for the synthesis of 2′-O-cyanoethyluridine, which is a key intermediate in the synthesis of fully and partially 2′-O-cyanoethylated oligoribonucleotides as well as unmodified oligoribonucleotides, was developed by the ring
A general method for the synthesis of 2′-O-cyanoethylated oligoribonucleotides having promising hybridization affinity for DNA and RNA and enhanced nuclease resistance
Saneyoshi, Hisao,Seio, Kohji,Sekine, Mitsuo
, p. 10453 - 10460 (2007/10/03)
An effective method for the synthesis of 2′-O-cyanoethylated oligoribonucleotides as a new class of 2′-O-modified RNAs was developed. The reaction of appropriately protected ribonucleoside derivatives with acrylonitrile in t-BuOH in the presence of Cssub