864837-22-9

Upstream product

• 872428-36-9 2'-O-(2-cyanoethyl)-5'-O-(4,4'-dimethoxytrityl)cytidine 3'-[2-cyanoethyl (N,N-diisopropyl)phosphoramidite] 
• 75-36-5 acetyl chloride 
• 864837-20-7 N⁴-acetyl-2'-O-(2-cyanoethyl)cytidine 
• 864837-19-4 2'-O-(2-cyanoethyl)cytidine 
• 864837-21-8 2'-O-(2-cyanoethyl)-4-N-acetyl-5'-O-(4,4'-dimethoxytrityl)cytidine 
• 124482-92-4 2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine 

Relevant academic research and scientific papers

Facile synthesis of 2′-O-cyanoethyluridine by ring-opening reaction of 2,2′-anhydrouridine with cyanoethyl trimethylsilyl ether in the presence of BF3·Et2O

In this Letter, a facile method for the synthesis of 2′-O-cyanoethyluridine, which is a key intermediate in the synthesis of fully and partially 2′-O-cyanoethylated oligoribonucleotides as well as unmodified oligoribonucleotides, was developed by the ring

NOVEL ARTIFICIAL RNAóS MODIFIED AT THE 2ó-HYDROXYL GROUP

The purpose of the present invention is to develop a system for efficiently constituting cyanoethyl ethers under mild conditions and probability of the ethers as functional groups for imparting specific functions and to make a contribution to the producti

A general method for the synthesis of 2′-O-cyanoethylated oligoribonucleotides having promising hybridization affinity for DNA and RNA and enhanced nuclease resistance

An effective method for the synthesis of 2′-O-cyanoethylated oligoribonucleotides as a new class of 2′-O-modified RNAs was developed. The reaction of appropriately protected ribonucleoside derivatives with acrylonitrile in t-BuOH in the presence of Cssub