864909-08-0Relevant articles and documents
Synthesis of substituted esters of imidazoles, oxazoles, thiazoles, and diethyl pyrazine-2,5-dicarboxylate from a common acyclic precursor employing C-formylation strategy
Khose, Goraksha,Shinde, Shailesh,Panmand, Anil,Kulkarni, Ravibhushan,Munot, Yogesh,Bandyopadhyay, Anish,Barawkar, Dinesh,Patil, Santoshkumar N.
supporting information, p. 2671 - 2674 (2014/05/06)
A novel synthetic route to substituted esters of imidazoles, oxazoles, thiazoles, and diethyl pyrazine-2,5-dicarboxylates via C-formylation of glycine ethyl ester hydrochloride is reported. This methodology is simple, robust, and gives good yields of different heterocyclic esters in one or two steps from a common acyclic precursor and is amenable to large scale synthesis.
Ion Channel Modulators
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Page/Page column 35, (2010/11/29)
The invention relates to compounds, compositions comprising the compounds, and methods of using the compounds and compound compositions. The compounds, compositions, and methods described herein can be used for the therapeutic modulation of ion channel function, and treatment of disease and disease symptoms, particularly those mediated by certain calcium channel subtype targets.
ION CHANNEL MODULATORS
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Page/Page column 58, (2010/02/14)
The invention relates to compounds, compositions comprising the compounds, and methods of using the compounds and compound compositions. The compounds, compositions, and methods described herein can be used for the therapeutic modulation of ion channel fu