865262-74-4

Upstream product

• 115156-56-4 (1R,2S,5R)-5-methyl-2-<1-methyl-1-(benzylamino)ethyl>cyclohexan-1-ol 
• 643-79-8 o-phthalic dicarboxaldehyde 

Downstream Products

• 915725-65-4 (1R,2'S,4a'S,7'R,8a'R)-1-(2-(N-benzyl-4',4',7'-trimethyl-octahydro-2H-benzo[e][1,3]oxazin-2'-yl)phenyl)-ethanol 
• 915725-66-5 (1R,2'S,4a'S,7'R,8a'R)-1-(2-(N-benzyl-4',4',7'-trimethyl-octahydro-2H-benzo[e][1,3]oxazin-2'-yl)phenyl)-propan-1-ol 
• 915725-68-7 (1R,2'S,4a'S,7'R,8a'R)-1-(2-(N-benzyl-4',4',7'-trimethyl-octahydro-2H-benzo[e][1,3]oxazin-2'-yl)phenyl)-but-3-en-1-ol 
• 865262-76-6 (2S,4aS,7R,8aR)-[2-(3-benzyl-4,4,7-trimethyl-octahydrobenzo[e][1,3]oxazin-2-yl)benzylidene]phenyl amine 
• 865262-78-8 (2S,4aS,7R,8aR)-[2-(N-benzyl-4,4,7-trimethyl-octahydrobenzo[e][1,3]oxazin-2-yl)benzylidene]-(4-methoxyphenyl) amine 
• 5398-11-8 3‐phenylisobenzofuran‐1(3H)‐one 
• 915725-76-7 (R)-1-Benzyl-3-ethoxy-1,3-dihydro-isobenzofuran 
• 915725-75-6 (R)-1-Ethoxy-3-phenyl-1,3-dihydro-isobenzofuran 
• 915725-67-6 (1R,2'S,4a'S,7'R,8a'R)-1-(2-(N-benzyl-4',4',7'-trimethyl-octahydro-2H-benzo[e][1,3]oxazin-2'-yl)phenyl)phenyl-methanol 
• 865262-99-3 (1R,2S,2'S,4a'S,5S,7S,7'R,8a'R)-2-[2-(N-benzyl-4',4',7'-trimethyl-octahydrobenzo[e][1,3]oxazin-2'-yl)phenyl]-6-phenyl-3-(4-methoxyphenyl)-10-oxa-3-azatricyclo[5.2.1.0^1,5]dec-8-en-4-one 
• 865263-11-2 (1R,2S,2'S,4a'S,5S,7S,7'R,8a'R)-2-[2-(N-benzyl-4',4',7'-trimethyl-octahydrobenzo[e][1,3]oxazin-2'-yl)phenyl]-5-methyl-3-(4-methoxyphenyl)-10-oxa-3-azatricyclo[5.2.1.0^1,5]decan-4-one 

Relevant academic research and scientific papers

Chiral template mediated diastereoselective intramolecular Diels-Alder reaction using furan as a diene. Toward the synthesis of enantiopure trisubstituted tetrahydroepoxyisoindolones

Chiral precursors to the intramolecular Diels-Alder reaction using furan as a diene (IMDAF) have been prepared by diastereoselective addition of furyllithium to imines attached to perhydro-1,3-benzoxazines derived from (-)-8-aminomenthol. The acylation of

A direct efficient diastereoselective synthesis of enantiopure 3-substituted-isobenzofuranones

Condensation of (-)-8-benzylaminomenthol with o-phthaldehyde lead to the chiral perhydro-1,3-benzoxazine 2 as single diastereoisomer. That compound reacted with different organometallics leading to 3 in excellent de. Hydrolysis of carbinols, followed by oxidation of the intermediates allowed for the synthesis of enantiopure phthalides.