865304-43-4

Basic information

• Product Name: 2-[5-(2,4-diaminopyrimidin-5-yloxy)-4-isopropyl-2-methoxy-phenyl]-propan-2-ol
• Synonyms: 2-[5-(2,4-diaminopyrimidin-5-yloxy)-4-isopropyl-2-methoxy-phenyl]-propan-2-ol
• CAS NO: 865304-43-4
• Molecular Weight: 332.403
• Mol File: 865304-43-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-[5-(2,4-diaminopyrimidin-5-yloxy)-4-isopropyl-2-methoxy-phenyl]-propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[5-(2,4-diaminopyrimidin-5-yloxy)-4-isopropyl-2-methoxy-phenyl]-propan-2-ol(865304-43-4)
• EPA Substance Registry System: 2-[5-(2,4-diaminopyrimidin-5-yloxy)-4-isopropyl-2-methoxy-phenyl]-propan-2-ol(865304-43-4)

Safety Data

• Hazardous Substances Data: 865304-43-4(Hazardous Substances Data)

Upstream product

• 865304-45-6 1-[5-(2,4-diamino-pyrimidine-5-yloxy)-4-isopropyl-2-methoxy-phenyl]-ethanol 
• 74-88-4 methyl iodide 
• 865304-28-5 1-[5-(2,4-diamino-pyrimidin-5-yloxy)-4-isopropyl-2-methoxy-phenyl]-ethanone 
• 75-16-1 methylmagnesium bromide 
• 865304-71-8 5-(2-isopropyl-4-methoxy-phenoxy)-pyrimidine-2,4-diamine 

Relevant articles and documents

METHODS AND COMPOSITIONS FOR TREATING DISEASES AND CONDITIONS

Provided herein include methods and compositions for treating diseases or conditions. In some embodiments provided are methods for treating one or more diseases or conditions selected from the group consisting of hypertension, heart failure, dyspnea, and

Methods of using diaminopyrimidine P2X3 and P2X2/3 receptor modulators for treatment of respiratory and gastrointestinal diseases

Methods for treating respiratory and gastrointestinal diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein D, X, Y, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein.