865593-96-0Relevant academic research and scientific papers
Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (part 2)
Huang, Horng-Chih,Tremont, Samuel J.,Lee, Len F.,Keller, Bradley T.,Carpenter, Andrew J.,Wang, Ching-Cheng,Banerjee, Shyamal C.,Both, Scott R.,Fletcher, Theresa,Garland, Danny J.,Huang, Wei,Jones, Claude,Koeller, Kevin J.,Kolodziej, Steve A.,Li, James,Manning, Robert E.,Mahoney, Matthew W.,Miller, Raymond E.,Mischke, Deborah A.,Rath, Nigam P.,Reinhard, Emily J.,Tollefson, Michael B.,Vernier, William F.,Wagner, Grace M.,Rapp, Steve R.,Beaudry, Judy,Glenn, Kevin,Regina, Karen,Schuh, Joe R.,Smith, Mark E.,Trivedi, Jay S.,Reitz, David B.
, p. 5853 - 5868 (2007/10/03)
In the preceding paper several compounds were reported as potent apical sodium-codependent bile acid transporter (ASBT) inhibitors. Since the primary site for active bile acid reabsorption is via ASBT, which is localized on the luminal surface of the dist
