865759-24-6

Basic information

• Product Name: 2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile
• Synonyms: 2-((6-chloro-3,4-dihydro-3-Methyl-2,4-dioxopyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile;2-[(6-chloro-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)methyl]-4-fluorobenzonitrile;2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile;Benzonitrile, 2-[(6-chloro-3,4-dihydro-3-Methyl-2,4-dioxo-1(2H)-pyriMidinyl)Methyl]-4-fluoro-;2-[(6-Chloro-3,4-dihydro-3-Methyl-2,4-dioxo-1(2H)-pyriMidinyl)Methyl]-4-fluorobenzonitrile
• CAS NO: 865759-24-6
• Molecular Formula: C₁₃H₉ClFN₃O₂
• Molecular Weight: 293.6808632
• Product Categories: Trelagliptin
• Mol File: 865759-24-6.mol
• Article Data: 29

Chemical Properties

• Boiling Point: 417.7±55.0 °C(Predicted)
• Appearance: /
• Density: 1.49±0.1 g/cm3(Predicted)
• PKA: -3.66±0.40(Predicted)
• CAS DataBase Reference: 2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile(865759-24-6)
• EPA Substance Registry System: 2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile(865759-24-6)

Safety Data

• Hazardous Substances Data: 865759-24-6(Hazardous Substances Data)

Usage

General Description

2-((6-chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile is a chemical compound with a complex structure. It contains a benzene ring with a cyano group and a fluorine atom attached, as well as a pyrimidine ring with a chlorine and a methyl group attached. 2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile may have potential applications in the pharmaceutical industry due to its unique structure, which could potentially be used to develop new drugs or treatments. Additionally, it may also be of interest to researchers in the field of organic chemistry for its complex and unique molecular structure. Further research and testing would be necessary to fully understand the properties and potential uses of this compound.

Upstream product

• 421552-12-7 2-(bromomethyl)-4-fluorobenzonitrile 
• 2565-47-1 1-methyl-2,4,6-pyrimidinetrione 
• 1261742-22-6 2-(chloromethyl)-4-fluorobenzonitrile 
• 4318-56-3 3-methyl-6-chlorouracil 
• 1000339-93-4 2-hydroxymethyl-4-fluorobenzonitrile 
• 147754-12-9 4-fluoro-2-methylbenzonitrile 
• 452-63-1 2-Bromo-5-fluorotoluene 

Downstream Products

• 1917324-13-0 (R)-2-({6-[3-({3-[(2-cyano-5-fluorophenyl)methyl]-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl}amino)piperidin-1-yl]-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1-yl}methyl)-4-fluorobenzonitrile 
• 928201-46-1 Trelagliptin hydrochloride 
• 1262205-80-0 (R)-2-((6-(3-amino-3-methylpiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile trifluoroacetate 
• 928201-45-0 Trelagliptin trifluoroacetate 

Relevant articles and documents

Identification, characterization and HPLC quantification of process-related impurities in Trelagliptin succinate bulk drug: Six identified as new compounds

A sensitive, selective and stability indicating reversed-phase LC method was developed for the determination of process related impurities of Trelagliptin succinate in bulk drug. Six impurities were identified by LC-MS. Further, their structures were char

Synthesis process of trelagliptin succinate

The present invention discloses a trelagliptin succinate synthesis process, and relates to the technical field of pharmaceutical chemical synthesis. In the process, 2-cyano-5-fluorobenzyl bromide and 6-chloro-3-methyl uracil are adopted as starting raw ma

Refining method of trelagliptin succinate

The invention discloses a refining method of trelagliptin succinate, which is characterized in that a trelagliptin succinate crude product (the purity is 99.76%) is used as an initial raw material, anorganic solvent is added into the trelagliptin succinat