86601-60-7Relevant academic research and scientific papers
Regioselective synthesis of substituted cyclohexa-1,3-dienes via the base-mediated cyclisation of α,β-unsaturated carbonyl compounds and γ-phosphonylcrotonates
Chandra, Rajesh,Joshi, Prabhakar R.,Menon, Rajeev S.
supporting information, (2020/09/04)
The base-mediated reaction of α,β-unsaturated carbonyl compounds and γ-phosphonylcrotonates under an argon atmosphere readily furnishes substituted cyclohexa-1,3-dienes. The cyclisation proceeds with complete regioselectivity to afford products that are r
Oxygenative and Dehydrogenative [3 + 3] Benzannulation Reactions of α,β-Unsaturated Aldehydes and γ-Phosphonyl Crotonates Mediated by Air: Regioselective Synthesis of 4-Hydroxybiaryl-2-carboxylates
Joshi, Prabhakar Ramchandra,Nanubolu, Jagadeesh Babu,Menon, Rajeev S.
, p. 752 - 755 (2016/03/01)
Regioselective synthesis of 4-hydroxybiphenyl-2-carboxylates via the base-mediated oxygenative [3 + 3] benzannulation reaction of α,β-unsaturated aldehydes and γ-phosphonyl crotonates is reported. A hydroxyl group is installed in the final product on the originally phosphorus-bound carbon via a novel oxygenative and dehydrogenative transformation. The reaction proceeds rapidly in an open flask, uses atmospheric oxygen as an oxidant, and affords good yields of substituted biaryl phenols. (Chemical Equation Presented).
Tandem Michael addition/ylide olefination reaction for the synthesis of highly functionalized cyclohexadiene derivatives
Ye, Long-Wu,Han, Xun,Sun, Xiu-Li,Tang, Yong
, p. 8149 - 8154 (2008/12/21)
A tandem Michael addition/ylide olefination for the rapid creation of highly functionalized cyclohexadiene is developed. The tandem annulation reactions afford versatile cyclohexadienes in good to excellent isolated yields. This method has been successfully applied to the synthesis of three biologically active molecules.
