86604-05-9

Usage

Uses

Used in Food and Beverage Industry:
4-Isopropylcinnamaldehyde is used as a flavoring agent for its distinctive aroma and taste, enhancing the sensory experience of various food and beverage products.
Used in Perfume and Cosmetic Industry:
As a fragrance, 4-Isopropylcinnamaldehyde is incorporated into perfumes and cosmetics for its pleasant and long-lasting scent, adding value to these personal care products.
Used in Pharmaceutical Industry:
4-Isopropylcinnamaldehyde is utilized for its anti-inflammatory, antioxidant, and antimicrobial properties, making it a potential candidate for the development of new drugs and treatments.
Used in Personal Care Industry:
4-ISOPROPYLCINNAMALDEHYDE is employed in personal care products for its beneficial properties, such as reducing inflammation and combating oxidative stress, thus contributing to skin health and wellness.
Used in Chemical Synthesis:
4-Isopropylcinnamaldehyde serves as a key intermediate in the synthesis of other compounds, playing a crucial role in the creation of various chemical products.
It is important to handle 4-isopropylcinnamaldehyde with care due to its potential irritant and sensitizing effects, ensuring safety in its applications across different industries.

Upstream product

• 876473-87-9 3-chloro-1-(4-isopropyl-phenyl)-propene 
• 64-17-5 ethanol 
• 100-97-0 hexamethylenetetramine 
• 27546-49-2 4-isopropyl-1-cyclopropylbenzene 
• 29805-21-8 1-(4-isopropylphenyl)-2-propyn-1-ol 
• 86657-74-1 1-Isopropyl-4-(1,3,3-triethoxy-propyl)-benzene 
• 274907-08-3 (E)-3-(4-isopropylphenyl)-2-propen-1-ol 
• 128408-02-6 ethyl (E)-3-(4-isopropylphenyl)-2-propenoate 
• 98-82-8 Isopropylbenzene 
• 123-38-6 propionaldehyde 
• 67785-72-2 dimethoxycymene 
• 122-03-2 (4-isopropylbenzaldehyde) 
• 86657-68-3 1-(4-Isopropyl-phenyl)-2-(4,4,6-trimethyl-5,6-dihydro-4H-[1,3]oxazin-2-yl)-ethanol 

Downstream Products

• 7402-35-9 4-isopropyl-cinnamaldehyde-(4-isobutyl thiosemicarbazone) 
• 351536-36-2 (E)-1,1,1-Trichloro-4-(4-isopropyl-phenyl)-but-3-en-2-ol 
• 351536-17-9 2-tert-butyldimethylsilyloxy-1,1,1-trichloro-4-(4-isopropylphenyl)-3-butene 
• 1208865-03-5 (R)-2-(3-oxo-1-(4-isopropylphenyl)propyl)malonic acid dibenzyl ester 
• 1208865-02-4 (S)-2-(3-oxo-1-(4-isopropylphenyl)propyl)malonic acid dibenzyl ester 

Relevant academic research and scientific papers

Amino acid derivative, feed composition and application thereof

The invention provides an amino acid derivative, a feed composition and application thereof, and belongs to the technical field of animal feed additives. The amino acid derivative is a compound with astructure shown as a formula (I), and a stereoisomer, a tautomer, a solvate, a metabolite, a feed acceptable salt or a prodrug thereof. In formula (I) shown in the specification, Z is a C1-C3 alkylene group. X is an indole ring group with a structure shown as a formula (II). The formula (II) is shown in the specification, wherein Y is phenyl with the structure shown in the formula (III) shown inthe specification. The amino acid derivative is used as an animal feed additive, and can promote the growth of animals and improve the feed conversion.

Iron(III)/O2-Mediated Regioselective Oxidative Cleavage of 1-Arylbutadienes to Cinnamaldehydes

A simple, efficient, and environmentally benevolent regioselective oxidative cleavage of 1-arylbutadienes to cinnamaldehydes mediated by iron(III) sulfate/O2 has been developed. The reaction offered good yields and excellent regioselectivity and showed good functional group tolerance (31 examples). The method is important, as few reports with limited substrate scope are available for such excellent oxidative cleavage of conjugated dienes.

Dehydrogenative β-Arylation of Saturated Aldehydes Using Transient Directing Groups

An unprecedented cross-dehydrogenative-coupling (CDC) reaction of saturated aldehyde β-C-H with arenes to form cinnamaldehydes via the cleavages of four C-H bonds has been developed. The reaction possesses complete E-stereoselectivity for the C=C double bond. The protocol is featured by atom and step economy, mild reaction conditions, and convenient operation.

HETEROAROMATIC COMPOUNDS HAVING SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR AGONIST BIOLOGICAL ACTIVITY

A novel compound having agonist activity at the S1P3 receptor which is represented by the formula I wherein X is selected from the group consisting of CR3, N and NO;Y is selected from the group consisting of CR3, N and NO;Z is selected from the group consisting of CR3, N and NO; and at least one of X, Y and Z is N or NO; V is O or NOR4 R1 is an aryl group;R2 is an aryl group;R3 is selected from the group consisting of H and alkyl; and 2 of said R3 groups may together form a cyclic alkyl ring having from 3 to 6 carbon atoms; R4 is selected from the group consisting of H and alkyl;a is 0 or an integer of from 1 to 6;b is 0 or 1;c is 0 or 1;f is 0 or an integer of 1 or 2;x is 0 or 1;y is 0 or an integer of from 1 to 3; andz is 0 or an integer of from 1 to 3.

Kinetic resolution of acyclic secondary allylic silyl ethers catalyzed by chiral ketones

Kinetic resolution of acyclic secondary allylic silyl ethers by chiral dioxiranes generated in situ from chiral ketones (R)-1 and (R)-2 and Oxone was investigated. An efficient and catalytic method has been developed for kinetic resolution of those substrates with a CCl3, tert-butyl, or CF3 group at the α-position. In particular, high selectivities (S up to 100) were observed for kinetic resolutions of racemic α-trichloromethyl allylic silyl ethers 7 and 9-15 catalyzed by ketones (R)-2. Both the recovered substrates and the resulting epoxides were obtained in high enantiomeric excess. On the basis of steric and electrostatic interactions between the chiral dioxiranes and the racemic substrates, a model was proposed to rationalize the enantioselectivities and diastereoselectivities in the chiral ketone-catalyzed kinetic resolution process.

PARA-ALKYL-SUBSTITUTED PHENYLCYCLOPROPANES IN REACTION WITH DINITROGEN TETROXIDE

The reaction of para-alkyl-substituted phenylcyclopropanes with dinitrogen tetroxide was studied.In solvents with various polarities at -30 deg C dinitrogen tetroxide only reacts with the three-carbon ring.Here the initially formed adducts are only stable at low temperatures; with increase in temperature they are converted into p-alkylcinnamaldehydes and 5-(p-alkylphenyl)isoxazolines.

PREFERENTIAL FORMATION OF THE Z ISOMERS OF CINNAMALDEHYDES IN THE REARRANGEMENT OF ARYLETHYNYLCARBINOLS CATALYZED BY POLYVANADIOORGANOSILOXANES

During the rearrangement of secondary and tertiary aryl(ethynyl)carbinols, catalyzed by polyvanadioorganosiloxanes, the thermodynamically less favorable Z isomers of the cinnamaldehydes are formed preferentially.It was shown that zero order in the initial carbinol and pseudofirst order in the catalyst are observed in the rearrangement.The activation parameters of the reaction, which confirm that the rearrangement takes place through a highly polar cyclic transition state, were determined.The dependence of the reaction rate on the structure of the initial carbinol is discussed.The Z-stereoselectivity of the rearrangement is explained by the presence of steric effects, which show up at the stage of the conversion of the intermediate allenyl vanadate into cinnamaldehyde.