86618-73-7

Upstream product

• 79-37-8 oxalyl dichloride 
• 81282-82-8 4-(3,5-dimethyl-1H-pyrazol-1-yl)benzoic acid 
• 619-67-0 4-Hydrazinobenzoic acid 
• 123-54-6 acetylacetone 

Downstream Products

• 86618-66-8 2,4-di-<4-(3,5-dimethyl-1(H)-pyrazole)benzoyloxy>acetophenone 
• 86618-67-9 2,4,6-tri-<4-(3,5-dimethyl-1(H)-pyrazole)benzoyloxy>acetophenone 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 
• 81282-68-0 2-<4-(3,5-dimethyl-1(H)-pyrazole)benzoyloxy>acetophenone 
• 220461-34-7 [4-(3,5-Dimethyl-pyrazol-1-yl)-phenyl]-(5H,11H-pyrrolo[2,1-c][1,4]-benzodiazepin-10-yl)-methanone 
• 86618-69-1 C₄₄H₃₈N₆O₇ 
• 86618-68-0 4-(3,5-Dimethyl-pyrazol-1-yl)-benzoic acid 4-{3-[4-(3,5-dimethyl-pyrazol-1-yl)-phenyl]-3-oxo-propionyl}-3-hydroxy-phenyl ester 
• 81282-76-0 1-[4-(3,5-Dimethyl-pyrazol-1-yl)-phenyl]-3-(2-hydroxy-phenyl)-propane-1,3-dione 

Relevant academic research and scientific papers

A General Method for Aminoquinoline-Directed, Copper-Catalyzed sp2 C-H Bond Amination

An operationally simple and general method for copper-catalyzed, aminoquinoline-assisted amination of β-C(sp2)-H bonds of benzoic acid derivatives is reported. The reaction employs Cu(OAc)2 or (CuOH)2CO3 catalysts, an amine coupling partner, and oxygen from air as a terminal oxidant. Exceptionally high generality with respect to amine coupling partners is observed. Specifically, primary and secondary aliphatic and aromatic amines, heterocycles, such as indoles, pyrazole, and carbazole, sulfonamides, as well as electron-deficient aromatic and heteroaromatic amines are competent coupling components.

Tricyclic vasopressin agonists

This invention relates to new compounds selected from those of the general formula (I), or a pharmaceutically acceptable salt, ester or prodrug form thereof: wherein D, E and G are N or CH, which serve as vasopressin agonists and are useful in treating disorders such as diabetes insipidus, nocturnal enuresis, nocturia, urinary incontinence, bleeding and coagulation disorders, and the inability to temporarily delay urination and pharmaceutical compositions and methods for same.