86633-14-9Relevant academic research and scientific papers
Enantioselective total syntheses and absolute configuration of JBIR-02 and Mer-A2026B
Hoecker, Johannes,Gademann, Karl
supporting information, p. 670 - 673 (2013/04/10)
The first total syntheses of the piericidin related natural products Mer-A2026B and JBIR-02 are reported. Key features of the synthetic approach involve an Ir-catalyzed one-pot C-H activation/oxidation procedure for the preparation of the hydroxypyridine, a vinylogous Mukaiyama aldol reaction, and a final Negishi cross-coupling of an advanced pyridine derivative with an allylic side chain precursor. In addition, the absolute configuration of Mer-A2026B (9R,10R) and JBIR-02 (9R,10R) was established.
PIPERAZINYL ANTIVIRAL AGENTS
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Page/Page column 213-214, (2011/04/25)
Provided are compounds of Formula (I) and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and their use for treating viral infections mediated by a member of the Flaviviridae family of viruses such as hepatitis C virus (HCV).
BENZIMIDAZOLE ANTIVIRAL AGENTS
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Page/Page column 134-135, (2011/09/14)
Provided are compounds of Formula (I) and (II) and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and their use for treating viral infections mediated by a member of the Flaviviridae family of viruses such as hepatitis C virus (HCV).
PIPERIDINYL CYCLIC AMIDO ANTIVIRAL AGENTS
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Page/Page column 124-125, (2010/08/18)
Provided are compounds of Formula (I) and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and their use for treating viral infections mediated by a member of the Flaviviridae family of viruses such as hepatitis C virus (HCV).
THERMAL DECOMPOSITION OF ORGANOTIN SULFAMATES: A ONE POT SYNTHESIS OF VINYLTRIBUTYLTIN COMPOUNDS
Ratier, Max,Khatmi, Djamel,Duboudin, J.Georges,Minh, Dao The
, p. 285 - 292 (2007/10/02)
The preparation of some alkyltributyltin sulfamates is described.Thermal decomposition of these compounds provides a route to vinyltributyltin derivatives.
Synthese et thermolyse eclair d'esters α-tributylstanniques
Duboudin, J. Georges,Ratier, Max,Trouve, Bruno
, p. 181 - 192 (2007/10/02)
The preparation of some alkyltributyltin acetates and thiocarbonates is described.Flash thermolysis of these compounds at high temperature (600-950 deg C) and under a moderate vacuum, provides a new route to vinyltributyltin derivatives.
A NEW ROUTE TO VINYLTRIBUTYLTIN COMPOUNDS BY FLASH PYROLYSIS OF ALKYLTRIBUTYLTIN ACETATES
Duboudin, J. Georges,Petraud, Michel,Ratier, Max,Trouve, Bruno
, p. C6 - C8 (2007/10/02)
Flash pyrolysis of alkyltributyltin acetates, at high temperatures (600-850 deg C) under a moderate vacuum provides a convenient route to vinyltin derivatives.
