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5-(2-methanesulfonyl-pyrimidin-4-yl)-thiophene-2-carboxylic acid [2-(2,4-dichloro-phenyl)-ethyl]-amide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

866523-72-0

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866523-72-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 866523-72-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,6,5,2 and 3 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 866523-72:
(8*8)+(7*6)+(6*6)+(5*5)+(4*2)+(3*3)+(2*7)+(1*2)=200
200 % 10 = 0
So 866523-72-0 is a valid CAS Registry Number.

866523-72-0Relevant academic research and scientific papers

Discovery of 2-pyrimidyl-5-amidothiophenes as potent inhibitors for AKT: Synthesis and SAR studies

Lin, Xiaodong,Murray, Jeremy M.,Rico, Alice C.,Wang, Michael X.,Chu, Daniel T.,Zhou, Yasheen,Rosario, Merci Del,Kaufman, Susan,Ma, Sylvia,Fang, Eric,Crawford, Kenneth,Jefferson

, p. 4163 - 4168 (2007/10/03)

A series of 2-pyrimidyl-5-amidothiophenes has been synthesized and evaluated for AKT inhibition. SAR studies resulted in potent inhibitors of AKT with IC50 values as low as single digit nanomolar as represented by compound 2aa. Compound 2aa sho

SUBSTITUTED THIOPHENE DERIVATIVES AS ANTI-CANCER AGENTS

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Page/Page column 92-93, (2008/06/13)

The present invention relates to new substituted five-membered compounds and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds

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