866724-08-5Relevant academic research and scientific papers
O6-Alkylguanine DNA Alkyltransferase Repair Activity Towards Intrastrand Cross-Linked DNA is Influenced by the Internucleotide Linkage
O'Flaherty, Derek K.,Wilds, Christopher J.
, p. 576 - 583 (2016)
Oligonucleotides containing an alkylene intrastrand cross-link (IaCL) between the O6-atoms of two consecutive 2′-deoxyguanosines (dG) were prepared by solid-phase synthesis. UV thermal denaturation studies of duplexes containing butylene and he
The synthesis of a menthol derivative of 2-aminopurine as a fluorescent DNA lesion
Hogendorf, Wouter F.J.,Verhagen, Carlo P.,Malta, Erik,Goosen, Nora,Overkleeft, Herman S.,Filippov, Dmitri V.,Van der Marel, Gijsbert A.
experimental part, p. 10430 - 10435 (2010/03/01)
An efficient synthetic route to the phosphoramidite of a menthol functionalized guanosine analog is presented. Two procedures were executed for the key introduction of the 6′-allyl menthyl moiety. Stille vinylation on 6-O-tosylguanosine followed by cross-
Synthesis of oligodeoxynucleotides incorporating 2-N-carbamoylguanine and evaluation of the hybridization properties
Sasami, Takeshi,Odawara, Yoko,Ohkubo, Akihiro,Sekine, Mitsuo,Seio, Kohji
experimental part, p. 1398 - 1403 (2009/07/11)
Previously, we reported 2-N-carbamoylguanine (cmG) as a guanine analog. We further studied the synthetic protocol and hybridization properties of oligodeoxynucleotides (ODNs) incorporating cmG. These ODNs were synthesized using the phosphoramidite of cmG
