1323344-95-1

Basic information

• Product Name: 3’-O-(tert-butyldimethylsilyl)-N²-phenoxyacetyl-2’-deoxyguanosine
• Synonyms: 3’-O-(tert-butyldimethylsilyl)-N²-phenoxyacetyl-2’-deoxyguanosine
• CAS NO: 1323344-95-1
• Molecular Weight: 515.641
• Mol File: 1323344-95-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3’-O-(tert-butyldimethylsilyl)-N²-phenoxyacetyl-2’-deoxyguanosine(CAS DataBase Reference)
• NIST Chemistry Reference: 3’-O-(tert-butyldimethylsilyl)-N²-phenoxyacetyl-2’-deoxyguanosine(1323344-95-1)
• EPA Substance Registry System: 3’-O-(tert-butyldimethylsilyl)-N²-phenoxyacetyl-2’-deoxyguanosine(1323344-95-1)

Safety Data

• Hazardous Substances Data: 1323344-95-1(Hazardous Substances Data)

Upstream product

• 866724-08-5 3’,5’-O-bis(tert-butydimethylsilyl)-N²-phenoxyacetyl-2’-deoxyguanosine 
• 110522-81-1 5’-O-dimethoxytrityl-N²-phenoxyacetyl-2’-deoxyguanosine 
• 642462-83-7 3’-O-(tertbutyldimethylsilyl)-5’-O-(4,4’-dimethoxytrityl)-N2-phenoxyacetyl-2’-deoxyguanosine 

Downstream Products

• 578-76-7 7-methylguanine 

Relevant articles and documents

BODIPY-modified 2′-deoxyguanosine as a novel tool to detect DNA damages

BODIPY-modified 2′-deoxyguanosine was synthesized for use as a detection reagent for genotoxic compounds. BODIPY-FL is a well known fluorescence reagent whose fluorescent light emission diminishes near a guanine base by a photo-induced electron transfer process. We attached BODIPY-Fl to the 5′ position of the deoxyribose moiety of 2′-deoxyguanosine. Although this compound has low fluorescence activity, when depurination by the action of alkylating reagents and dG oxidation by singlet oxygen occurred, the emission of strong fluorescence was observed. BODIPY-dG was found, therefore, to be a very useful tool for selectively detecting DNA damaging activity particularly in natural environmental extracts.