866785-24-2Relevant articles and documents
Camphor sulfonamide derivatives as novel, potent and selective CXCR3 antagonists
Wang, Yonghui,Busch-Petersen, Jakob,Wang, Feng,Kiesow, Terence J.,Graybill, Todd L.,Jin, Jian,Yang, Zheng,Foley, James J.,Hunsberger, Gerald E.,Schmidt, Dulcie B.,Sarau, Henry M.,Capper-Spudich, Elizabeth A.,Wu, Zining,Fisher, Laura S.,McQueney, Michael S.,Rivero, Ralph A.,Widdowson, Katherine L.
scheme or table, p. 114 - 118 (2009/04/16)
A series of N-arylpiperazine camphor sulfonamides was discovered as novel CXCR3 antagonists. The synthesis, structure-activity relationships, and optimization of the initial hit that resulted in the identification of potent and selective CXCR3 antagonists are described.
