866865-72-7Relevant academic research and scientific papers
Mapping the active site of the bacterial enzyme LpxC using novel carbohydrate-based hydroxamic acid inhibitors
Li, Xuechen,McClerren, Amanda L.,Raetz, Christian R. H.,Hindsgaul, Ole
, p. 583 - 609 (2005)
LpxC (UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc deacetylase), an enzyme involved in the biosynthesis of lipid A, is crucial for the growth of Gram-negative bacteria. This enzyme has accordingly been identified as a potential target for the development of nove
