86694-73-7

Upstream product

• 22118-09-8 2-bromoacetyl chloride 
• 81902-49-0 diethyl N-(2,4-dimethoxybenzyl)-amino-malonate 
• 86694-72-6 diethyl N-(2,4-dimethoxy-benzyl)-N-(chloroacetyl)-amino-malonate 

Downstream Products

• 86694-74-8 ethyl 1-(2,4-dimethoxybenzyl)-4-oxo-2-azetidine-carboxylate 
• 613-45-6 2,4-Dimethoxybenzaldehyde 
• 91921-99-2 1-(2,4-dimethoxybenzyl)-4-oxoazetidine-2-carboxylic acid 
• 91922-01-9 4-(cyanomethyl)-1-(2,4-dimethoxybenzyl)-2-azetidinone 
• 103841-23-2 1-(2,4-dimethoxybenzyl)-4-oxoazetidine-2-carboxylic acid benzhydryl ester 
• 86694-76-0 1-(2,4-dimethoxy-benzyl)-4-(mesyloxymethyl)-2-azetidinone 
• 103864-98-8 4-cyanomethyl-1-(2,4-dimethoxybenzoyl)azetidin-2-one 
• 87260-79-5 1-(2,4-dimethoxy-benzyl)-4-(iodomethyl)-2-azetidinone 
• 94271-43-9 ethyl 4-oxoazetidine-2-carboxylate 
• 86694-75-9 1-(2,4-dimethoxy-benzyl)-4-(hydroxymethyl)-2-azetidinone 

Relevant academic research and scientific papers

Anti-tumor platinum complexes, their preparation and their therapeutic use

Compounds of formula (I): STR1 in which: A and B are separately monoamines or together diamines; and Z is a group of formula (II) or (III): STR2 (in which R1, R2 and R7 are various organic groups, n is 0, 1 or 2 and X is a

Heterocyclic compounds containing an alkoxycarbonyl and a substituted methyl group

The invention relates to new heterocyclic compound containing an alkoxycarbonyl and a substituted methyl group a process for the preparation of these and analogeous compound and pharmaceutical compositions containing them. More particularly, the invention concerns compounds of the general formula (IVa) STR1 wherein R' is hydrogen, 2-ethoxycarbonylethyl, aryl or a group suitable for a temporary protection of amides and Y' represents a group of the formula --COOZ or --CH2 M, in which Z is lower alkyl and M is hydroxyl, halogen, cyano or a group of the formula --O--SO2 R2, in which R2 is lower alkyl or aryl, with the proviso that if R' is phenyl, Y' cannot stand for the group --COOC2 H5. The invention further relates to a process for the preparation of compounds of the general formula (IV) STR2 in which R and Y are identical with R' and Y', respectively, except the proviso. According to a further aspect of the invention there are provided pharmaceutical compositions, first of all with antihypoxic activity, comprising compounds of the general formula (IVa) as active ingredient.