867060-65-9Relevant academic research and scientific papers
Synthesis of aryl-1,2,4-triazine-3,5-diones as antagonists of the gonadotropin-releasing hormone receptor
Pontillo, Joseph,Guo, Zhiqiang,Wu, Dongpei,Struthers, R. Scott,Chen, Chen
, p. 4363 - 4366 (2007/10/03)
Several efficient synthetic routes for 2-, 4-, and 6-aryl-1,2,4-triazine-3, 5-diones were developed. Derivatives were synthesized and studied as gonadotropin-releasing hormone antagonists in an effort to understand structure-activity relationships of the monocyclic compounds.
