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1-[4-(CHLOROMETHYL)PHENYL]-1H-IMIDAZOLE HYDROCHLORIDE, also known as Clonactin, is a potent imidazole-based antifungal agent primarily used for treating superficial fungal infections. It functions by inhibiting the synthesis of ergosterol, a crucial component of fungal cell membranes, which results in increased membrane permeability and cell death.
Used in Pharmaceutical Industry:
1-[4-(CHLOROMETHYL)PHENYL]-1H-IMIDAZOLE HYDROCHLORIDE is used as an antifungal agent for the treatment of superficial fungal infections. It is effective against a broad range of fungal species, including dermatophytes and yeast, due to its ability to disrupt the synthesis of ergosterol, leading to cell death.
Used in Topical Medications:
1-[4-(CHLOROMETHYL)PHENYL]-1H-IMIDAZOLE HYDROCHLORIDE is used as an active ingredient in topical creams or solutions for the targeted application on affected skin areas. This allows for localized treatment of fungal infections with minimal systemic absorption, reducing the risk of side effects.
Used with Caution in Certain Patient Populations:
1-[4-(CHLOROMETHYL)PHENYL]-1H-IMIDAZOLE HYDROCHLORIDE is used with caution in patient populations that may be more susceptible to skin irritation or systemic absorption. Short-term use is recommended to minimize potential adverse effects.

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  • 86718-09-4 Structure
  • Basic information

    1. Product Name: 1-[4-(CHLOROMETHYL)PHENYL]-1H-IMIDAZOLE HYDROCHLORIDE
    2. Synonyms: 1-[4-(CHLOROMETHYL)PHENYL]-1H-IMIDAZOLE HYDROCHLORIDE
    3. CAS NO:86718-09-4
    4. Molecular Formula: C10H9ClN2*ClH
    5. Molecular Weight: 229.11
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 86718-09-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Sealed in dry,Room Temperature
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-[4-(CHLOROMETHYL)PHENYL]-1H-IMIDAZOLE HYDROCHLORIDE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-[4-(CHLOROMETHYL)PHENYL]-1H-IMIDAZOLE HYDROCHLORIDE(86718-09-4)
    11. EPA Substance Registry System: 1-[4-(CHLOROMETHYL)PHENYL]-1H-IMIDAZOLE HYDROCHLORIDE(86718-09-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 86718-09-4(Hazardous Substances Data)

86718-09-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 86718-09-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,7,1 and 8 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 86718-09:
(7*8)+(6*6)+(5*7)+(4*1)+(3*8)+(2*0)+(1*9)=164
164 % 10 = 4
So 86718-09-4 is a valid CAS Registry Number.

86718-09-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(4-(Chloromethyl)phenyl)-1H-imidazole hydrochloride

1.2 Other means of identification

Product number -
Other names 1-[4-(chloromethyl)phenyl]imidazole,hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:86718-09-4 SDS

86718-09-4Relevant articles and documents

N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohept (B) indole

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, (2008/06/13)

The invention provides new N-imidazolyl derivatives of substituted tetrahydrocarbazoles and cyclopent[b]indoles of general formula (I) STR1 wherein n is 1 or 2; p is an integer of 1 to 4; A is a straight or branched C1 -C4 alkylene c

Novel N-(3-hydroxy-4-piperidinyl)benzamide derivatives

-

, (2008/06/13)

Novel N-(3-hydroxy-4-piperidinyl)benzamides and derivatives thereof, said compounds being useful as stimulators of the motility of the gastro-intestinal system.

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