867367-88-2Relevant academic research and scientific papers
SYNTHESIS OF RESORCYLIC ACID LACTONES USEFUL AS THERAPEUTIC AGENTS
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Page/Page column 97, (2009/08/16)
Disclosed are macrocyclic compounds of formulae I, I', II, II', III, III', IV, and V, which are analogs of the pochonin resorcylic acid lactones, pharmaceutical compositions comprising the compounds, and methods and uses comprising the compounds for the t
Solution- and solid-phase synthesis of radicicol (monorden) and pochonin C
Barluenga, Sofia,Moulin, Emilie,Lopez, Pilar,Winssinger, Nicolas
, p. 4935 - 4952 (2007/10/03)
A modular synthesis for pochonin C and radicicol is reported. The two natural products were prepared in seven and eight steps, respectively, from three readily available fragments. Alternative syntheses of these compounds were achieved using a combination of polymer-bound reagents and solid phase reactions. The conformation of the two natural products was studied and compared by using 2D NMR spectroscopy.
