867374-53-6

Usage

Uses

Used in Organic Synthesis:
2-bromo-7-iodofluoren-9-one is used as a reagent for the introduction of bromine and iodine into organic molecules, facilitating the synthesis of various complex organic compounds.
Used in Chemical Research:
2-bromo-7-iodofluoren-9-one is utilized in chemical research to study its reactivity and explore its potential applications in different fields.
Used in Pharmaceutical Development:
2-bromo-7-iodofluoren-9-one is studied for its potential applications in pharmaceuticals, given its unique properties that may contribute to the development of new drugs.
Used in Materials Science:
2-bromo-7-iodofluoren-9-one is also being investigated for its possible use in materials science, where its reactivity and properties could be leveraged to create novel materials with specific characteristics.
It is crucial to handle and use 2-bromo-7-iodofluoren-9-one with caution due to its potential hazards, ensuring proper safety measures are in place during its application in various industries.

Upstream product

• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 3096-46-6 2-iodofluorenone 
• 123348-27-6 2-bromo-7-iodofluorene 
• 1133-80-8 2-bromo-9H-fluorene 
• 3096-56-8 2-bromofluoren-9-one 

Relevant academic research and scientific papers

Amphiphilic ligands for Cu-catalyzed aerobic oxidation to synthesize 9-fluorenones in water

A series of amphiphilic PEG-functionalized nitrogen ligands were developed for the highly efficient copper-catalyzed aerobic oxidation of 9-fluorenes, with molecular oxygen as the sole oxidant in neat water. A broad range of functional groups are well tolerated and thus offer the opportunity for further functionalization.

Method for synthesizing fluorenone ketone compound through molecular oxygen oxidation in water phase

Aiming at the technical problems that in the prior art a method for synthesizing a fluorenone ketone compound has organic solvent pollution and byproducts can be generated, the invention provides a method for synthesizing a fluorenone ketone compound through molecular oxygen oxidation in a water phase. The method comprises the following steps: by taking a fluorenone compound as a substrate, dispersing into an alkali solution, and at 40-120 DEG C, in the presence of oxygen, and with a water-soluble transition metal compound as a catalyst, stirring to carry out reactions, thereby obtaining the fluorenone ketone compound. By adopting the method, molecular oxygen is adopted as an oxidant, and water is adopted as a solvent, so that an organic solvent is avoided, and the problem that multiple byproducts are generated because of peroxidation can be avoided.

Transition-metal-free C(sp3)–H oxidation of diarylmethanes

An efficient direct C(sp3)–H oxidation of diarylmethanes has been demonstrated by this study. This method employs environment-friendly O2 as an oxidant and is promoted by commercially available MN(SiMe3)2 [M = K, Na or Li], which provides a facile method for the synthesis of various diaryl ketones in excellent yields. This protocol is metal-free, mild and compatible with a number of functional groups on substrates.

Cu(II)-Catalyzed Ligand-Free Oxidation of Diarylmethanes and Second Alcohols in Water

We developed a simple and efficient Cu(II)-catalyzed ligand-free oxidation of diarylmethanes and secondary alcohols using 70% tert-butyl hydroperoxide (TBHP) in water. A series of diarylmethanes were directly oxidized into diaryl ketones in 67%–98% yields. Additionally, various secondary alcohols were also transformed into the desired products in 48%–98% yields. Importantly, the catalytic system in the absence of any organic solvent, surfactant, or phase transfer agent, had a wide substrate scope and a high tolerance for various functional groups.

Method of fluorination multi-substituted fluorene derivatives (by machine translation)

The invention discloses a method of fluorination, fluorenone derivatives can be (9) or (6) conveniently converted to 2-bromo-7-iodo -9,9-difluoro -9H-fluorenylmethylchloroformate (1) or 2,7-dibromo -9,9-difluoro -9H-fluorenylmethylchloroformate (3) [...] derivatives, and the like. (by machine translation)

Synthesis of molecular tripods based on a rigid 9,9'-spirobifluorene scaffold

The efficient synthesis of a new tripodal platform based on a rigid 9,9'-spirobifluorene with three acetyl protected thiol groups in the positions 2, 3' and 6' for deposition on Au(111) surfaces is reported. The modular 9,9'-spirobifluorene platform provi

Amino-substituted tricyclic derivatives and methods of use

Compounds of formula (I) wherein A and B are amine-substituted sidechains, Y1 and Y2 form various tricyclic cores, Xa and Xb are C, CH, or N, as defined herein, and Rx is an optional substituent. Compounds and compositions of formula (I) are contemplated as well as methods for treating conditions or disorders prevented by or ameliorated by α7nAChR ligands that encompass compounds of formula (I) and other tricyclic derivatives. Methods of using amino-substituted tricyclic derivatives also are described herein.